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Meta-analysis is a method of synthesis of quantitative data from multiple independent studies addressing a common research question. An important part of this method involves computing a combined effect size across all of the studies.
The aim of the PRISMA statement is to help authors improve the reporting of systematic reviews and meta-analyses. [3] PRISMA has mainly focused on systematic reviews and meta-analysis of randomized trials, but it can also be used as a basis for reporting reviews of other types of research (e.g., diagnostic studies, observational studies).
In medical research, an umbrella review is a review of systematic reviews or meta-analyses. [1] [2] [3] They may also be called overviews of reviews, reviews of reviews, summaries of systematic reviews, or syntheses of reviews. [1] Umbrella reviews are among the highest levels of evidence currently available in medicine. [2]
A meta-regression can be classified in the same way—meta-regression and network meta-regression—depending on the number of distinct treatments in the regression analysis. Meta-analysis (and meta-regression) is often placed at the top of the evidence hierarchy provided that the analysis consists of individual participant data of randomized ...
This measure of effect has greater precision (less uncertainty) than the individual studies, but it may be biased by differences between the studies in study design, the type of evidence, or other key characteristics. [4] In qualitative research, methods of synthesis include narrative synthesis and meta-ethnography. Narrative synthesis allows ...
In an IPD meta-analysis, patient-level data from multiple studies or settings are combined to address a certain research question. IPD meta-analyses tend to be common for large-scale and international projects, and they are less limited than aggregate data (AD) meta-analyses in terms of the availability and quality of data they can use. [2]
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CMA does not solve meta-analysis's problem of "garbage in, garbage out". However, when a class of studies is deemed garbage by a critic, it does offer a way of examining the extent to which those studies may have changed a result. Similarly, it offers no direct solution to the problem of which method to choose for combination or weighting.
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