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[4] [3] As such, testosterone cypionate and testosterone enanthate are considered to be "functionally interchangeable" as medications. [4] For reference, testosterone enanthate has an elimination half-life of 4.5 days and a mean residence time of 8.5 days and requires frequent administration of approximately once per week. [21]
[8] [33] The pharmacokinetics of testosterone cypionate are said to be the same as those of testosterone enanthate, with "extremely comparable" patterns of testosterone release. [ 35 ] [ 33 ] Due to their varying and different elimination half-lives, the different intramuscular testosterone esters are administered with differing frequencies. [ 74 ]
Testosterone enanthate is used primarily in androgen replacement therapy. [4] [15] It is the most widely used form of testosterone in androgen replacement therapy. [4]The medication is specifically approved, in the United States, for the treatment of hypogonadism in men, delayed puberty in boys, and breast cancer in women. [16]
Testosterone decanoate has been investigated as a potential long-acting injectable male contraceptive. [ 4 ] [ 6 ] [ 7 ] [ 8 ] It has a longer duration of action than testosterone enanthate , but its duration is not as prolonged as that of testosterone undecanoate .
Testosterone propionate (Testosterone Propionate (generic)), testosterone cypionate/estradiol cypionate (brand name Depo-Testadiol), testosterone enanthate/estradiol valerate (brand name Ditate-DS) as oil solutions for intramuscular injection were previously available but were discontinued.
Testosterone propionate/testosterone enanthate/testosterone undecylenate (TP/TE/TUe), sold under the brand name Durasteron, is an injectable combination medication of testosterone propionate (TP), testosterone valerate (TV), and testosterone undecylenate (TUe), all of which are androgens/anabolic steroids.
Structural properties of major testosterone esters; Androgen Structure Ester Relative mol. weight Relative T content b logP c; Position(s) Moiet(ies) Type Length a; Testosterone – – – – 1.00
Sustanon is the preferred method of testosterone replacement in the United Kingdom as detailed in the British National Formulary. [ citation needed ] There was a brief shortage of Sustanon 250 during late 2011, due to shifting of manufacturing site, [ 7 ] and a further shortage in mid-2012 due to manufacturing problems.
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