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A pathologic fracture is a bone fracture caused by weakness of the bone structure that leads to decrease mechanical resistance to normal mechanical loads. [1] This process is most commonly due to osteoporosis, but may also be due to other pathologies such as cancer, infection (such as osteomyelitis), inherited bone disorders, or a bone cyst.
Enchondroma is a type of benign bone tumor belonging to the group of cartilage tumors. [1] [2] There may be no symptoms, [3] or it may present typically in the short tubular bones of the hands with a swelling, pain or pathological fracture. [4] Diagnosis is by X-ray, CT scan and sometimes MRI. [4] Most occur as a less than three centimetre size ...
The most common bone tumor is a non-ossifying fibroma. [4] Average five-year survival in the United States after being diagnosed with bone and joint cancer is 67%. [5] The earliest known bone tumor was an osteosarcoma in a foot bone discovered in South Africa, between 1.6 and 1.8 million years ago. [6]
A broken finger or finger fracture is a common type of bone fracture, affecting a finger. [1] Symptoms may include pain, swelling, tenderness, bruising, deformity and reduced ability to move the finger. [2] Although most finger fractures are easy to treat, failing to deal with a fracture appropriately may result in long-term pain and disability ...
The tumor causes a great deal of pain, and can even lead to fracture of the affected bone. As with human osteosarcoma, bone biopsy is the definitive method to reach a final diagnosis. Osteosarcoma should be differentiated from other bone tumours and a range of other lesions, such as osteomyelitis .
Denosumab, sold under the brand names Prolia and Xgeva among others, is a human monoclonal antibody used for the treatment of osteoporosis, treatment-induced bone loss, metastases to bone, and giant cell tumor of bone.
Bone metastasis, or osseous metastatic disease, is a category of cancer metastases that result from primary tumor invasions into bones.Bone-originating primary tumors such as osteosarcoma, chondrosarcoma, and Ewing sarcoma are rare; the most common bone tumor is a metastasis. [1]
The brown tumor is a bone lesion that arises in settings of excess osteoclast activity, such as hyperparathyroidism. They are a form of osteitis fibrosa cystica. It is not a neoplasm, but rather simply a mass. It most commonly affects the maxilla and mandible, though any bone may be affected. [1] Brown tumours are radiolucent on x-ray.