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  2. Kindling (sedative–hypnotic withdrawal) - Wikipedia

    en.wikipedia.org/wiki/Kindling_(sedative...

    Repeated benzodiazepine withdrawal episodes may result in similar neuronal kindling as that seen after repeated withdrawal episodes from alcohol, with resultant increased neuro-excitability. The glutamate system is believed to play an important role in this kindling phenomenon with AMPA receptors which are a subtype of glutamate receptors being ...

  3. List of polysubstance combinations - Wikipedia

    en.wikipedia.org/wiki/List_of_polysubstance...

    Alcohol: Benzodiazepine: Time flip Time flipping Alcohol: Caffeine: Caffeinated alcoholic drink: Alcohol: Cannabis: Tincture of cannabis. Herb and Al. Judgement Day Cross fading, twisting, getting twisted [13] Called Judgement Day in Ghana when cannabis is added to the drink Alcohol: Cocaine: Snow-cone Snow-coning Ethanol is metabolized into ...

  4. Caffeine dependence - Wikipedia

    en.wikipedia.org/wiki/Caffeine_dependence

    Caffeine dependence can cause a host of physiological effects if caffeine consumption is not maintained. Withdrawal symptoms may include headaches, fatigue, difficulty concentrating, lack of motivation, mood swings, nausea, insomnia, dizziness, cardiac issues, hypertension, anxiety, backaches, and joint pain; these can range in severity from mild to severe. [18]

  5. Caffeinated alcoholic drink - Wikipedia

    en.wikipedia.org/wiki/Caffeinated_alcoholic_drink

    Anhydrous caffeine, the product of the decaffeination process. For many caffeinated alcoholic drinks, this is a primary source of caffeine. Sample of absolute ethanol. The main ingredients in caffeinated alcoholic drinks are alcohol and caffeine. The caffeine is often added by ingredients like energy drinks, coffee, tea, or dark chocolate.

  6. Alcohol withdrawal syndrome - Wikipedia

    en.wikipedia.org/wiki/Alcohol_withdrawal_syndrome

    These adverse effects are believed to be due to the neurotoxic effects of repeated withdrawal from alcohol on aberrant neuronal plasticity and cortical damage. Repeated periods of acute intoxication followed by acute detoxification has profound effects on the brain and is associated with an increased risk of seizures as well as cognitive deficits.

  7. Alcoholic hallucinosis - Wikipedia

    en.wikipedia.org/wiki/Alcoholic_hallucinosis

    Management with a combination of abstinence from alcohol and the use of neuroleptics has been shown to be effective. [11] It is also possible to treat withdrawal before major symptoms start to happen in the body. Diazepam and chlordiazepoxide have proven to be effective in treating alcohol withdrawal symptoms such as alcoholic hallucinosis ...

  8. Caffeine - Wikipedia

    en.wikipedia.org/wiki/Caffeine

    When alcohol and caffeine are consumed jointly, the effects of the caffeine are changed, but the alcohol effects remain the same. [157] For example, consuming additional caffeine does not reduce the effect of alcohol. [157] However, the jitteriness and alertness given by caffeine is decreased when additional alcohol is consumed. [157]

  9. Comedown (drugs) - Wikipedia

    en.wikipedia.org/wiki/Comedown_(drugs)

    The use of caffeine may also be subject to periods of low energy and mood following its effects. Stimulant comedowns are unique in that they often appear very abruptly after a period of focus or high, and are typically the more intensely dysphoric phase of withdrawal than that following complete elimination from the bloodstream.