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STP was first synthesized and tested in 1963 by Alexander Shulgin, who was investigating the effect of 4-position substitutions on psychedelic amphetamines. [3]In mid-1967, tablets containing 20 mg (later 10 mg) of STP were widely distributed in the Haight-Ashbury District of San Francisco under the name of STP, having been manufactured by underground chemists Owsley Stanley and Tim Scully.
Leprosy. Leprosy, also known as Hansen's disease (HD), is a long-term infection by the bacteria Mycobacterium leprae or Mycobacterium lepromatosis. [4][7] Infection can lead to damage of the nerves, respiratory tract, skin, and eyes. [4] This nerve damage may result in a lack of ability to feel pain, which can lead to the loss of parts of a ...
Dysentery. Dysentery (UK: / ˈdɪsəntəri / DISS-ən-tər-ee, [7] US: / ˈdɪsəntɛri / DISS-ən-terr-ee), [8] historically known as the bloody flux, [9] is a type of gastroenteritis that results in bloody diarrhea. [1][10] Other symptoms may include fever, abdominal pain, and a feeling of incomplete defecation. [2][6][11] Complications may ...
One of the potential side effects of treatment is the Jarisch–Herxheimer reaction. [3] It frequently starts within one hour and lasts for 24 hours, with symptoms of fever, muscle pains, headache, and a fast heart rate. [3] It is caused by cytokines released by the immune system in response to lipoproteins released from rupturing syphilis ...
Tuberculosis (TB), also known colloquially as the " white death ", or historically as consumption, [8] is an infectious disease usually caused by Mycobacterium tuberculosis (MTB) bacteria. [1] Tuberculosis generally affects the lungs, but it can also affect other parts of the body. [1] Most infections show no symptoms, in which case it is known ...
Patrilineal and matrilineal most recent common ancestors (MRCAs) of living humans roughly between 200 and 100 kya [55] [56] with some estimates on the patrilineal MRCA somewhat higher, ranging up to 250 to 500 kya. [57] 160,000 years ago, Homo sapiens idaltu in the Awash River Valley (near present-day Herto village, Ethiopia) practiced ...
2–3 per year (adults) 6–8 per year (children) [13] The common cold or the cold is a viral infectious disease of the upper respiratory tract that primarily affects the respiratory mucosa of the nose, throat, sinuses, and larynx. [6][8] Signs and symptoms may appear in as little as two days after exposure to the virus. [6]
Cyanide is a potent cytochrome c oxidase (COX, a.k.a. Complex IV) inhibitor, causing asphyxiation of cells. As such, cyanide poisoning is a form of histotoxic hypoxia, because it interferes with the ability of cells to take or use oxygen via oxidative phosphorylation. [25]: 1475. Specifically, cyanide binds to the heme a3-CuB binuclear center ...