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Famotidine, sold under the brand name Pepcid among others, is a histamine H 2 receptor antagonist medication that decreases stomach acid production. [4] It is used to treat peptic ulcer disease , gastroesophageal reflux disease , and Zollinger-Ellison syndrome . [ 4 ]
Proton-pump inhibitor. Proton-pump inhibitors (PPIs) are a class of medications that cause a profound and prolonged reduction of stomach acid production. They do so by irreversibly inhibiting the stomach's H + /K + ATPase proton pump. [1] Proton-pump inhibitors have largely superseded the H 2 -receptor antagonists, a group of medications with ...
Cimetidine is a histamine type 2 blocker, which also binds to the androgen receptor to inhibit its function." However, this antiandrogen activity of cimetidine is weak, and the clinical benefit of its use in women with hirsutism is minimal. Thus, this drug is not recommended for the treatment of hyperandrogenism.
Zantac was first marketed in 1981, [7] and it was described in 1989 as "one of the most expensive drugs on the market", [8] and "the world's biggest-selling prescription drug". [9] Addiction to taking it ("a habit") was how some of its users described Zantac. [10] The focus of Glaxo, its manufacturer, was to gain market share "from Zantac ...
Ranitidine has 10% of the affinity that cimetidine has to CYP450, so it causes fewer side effects, but other H 2 blockers famotidine and nizatidine have no CYP450 significant interactions. [ 131 ] Ranitidine was introduced in 1981, and was the world's biggest-selling prescription drug by 1987.
Jamie A. Koufman is a physician and researcher on the topic of acid reflux.She coined the terms "laryngopharyngeal reflux" and "silent reflux".[1]Koufman is the founder and director of the now defunct Voice Institute of New York, [2] a comprehensive voice and reflux treatment center, and Professor of Clinical Otolaryngology at New York Medical College.
Proton-pump inhibitors (PPIs) are a group of drugs whose main action is a pronounced and long-lasting reduction of gastric acid production. They are the most potent inhibitors of acid secretion available. The group followed and has largely superseded another group of pharmaceuticals with similar effects, but a different mode of action, called H ...
The word “DOPING” is printed in capital letters inside a red circle with a slash through it on the box containing the over-the-counter spray sold in Italy that caused No. 1-ranked tennis ...
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