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2- and 4-chloropyridine are prepared from the corresponding pyridinols using phosphoryl chloride. [1] Uses
4-Chloro-α-pyrrolidinovalerophenone (also known as 4-chloro-α-pyrrolidinopentiophenone, 4-chloro-α-PVP, 4Cl-PVP, or 4C-PVP, or alpha-PVP, or flakka) is an emerging recreational designer drug of the pyrrolidinophenone class, similar in structure to α-pyrrolidinopentiophenone (α-PVP). [1]
U-47700 is an agonist of the μ-opioid receptor (K i 11.1 ± 0.4 nM) and possesses significantly lower affinity for the κ-opioid receptor (K i = 287 ± 24 nM) and δ-opioid receptor (K i = 1220 ± 82 nM). U-47700 is approximately 10-fold more potent than morphine in rats, although the binding of U-47700 is 2–4 times weaker than morphine at ...
2-Bromopyridine reacts with butyllithium to give 2-lithiopyridine, [2] which is a versatile reagent. [3] Pyrithione can be prepared in a two-step synthesis from 2-bromopyridine by oxidation to the N-oxide with a suitable peracid followed by substitution using either sodium dithionite or sodium sulfide with sodium hydroxide to introduce the thiol functional group.
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2-Chloropyridine is an aryl chloride with the formula C 5 H 4 ClN. It is a colorless liquid that is mainly used to generate fungicides and insecticides in industry. It also serves to generate antihistamines and antiarrythymics for pharmaceutical purposes. [2] It is one of three isomers of chloropyridine.
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