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  2. Famotidine - Wikipedia

    en.wikipedia.org/wiki/Famotidine

    Famotidine, sold under the brand name Pepcid among others, is a histamine H 2 receptor antagonist medication that decreases stomach acid production. [4] It is used to treat peptic ulcer disease , gastroesophageal reflux disease , and Zollinger–Ellison syndrome . [ 4 ]

  3. H2 receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/H2_receptor_antagonist

    Cimetidine was the prototypical histamine H 2 receptor antagonist from which later drugs were developed. Cimetidine was the culmination of a project at Smith, Kline & French (SK&F; now GlaxoSmithKline) by James W. Black, C. Robin Ganellin, and others to develop a histamine receptor antagonist that would suppress stomach acid secretion.

  4. Ranitidine - Wikipedia

    en.wikipedia.org/wiki/Ranitidine

    Ranitidine has 10% of the affinity that cimetidine has to CYP450, so it causes fewer side effects, but other H 2 blockers famotidine and nizatidine have no CYP450 significant interactions. [ 131 ] Ranitidine was introduced in 1981, and was the world's biggest-selling prescription drug by 1987. [ 132 ]

  5. The Best Alternatives to Zantac, Which the FDA Just ... - AOL

    www.aol.com/news/best-alternatives-zantac-fda...

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  6. Sanofi to settle 4,000 Zantac cancer lawsuits in US state courts

    www.aol.com/news/sanofi-settle-4-000-zantac...

    NEW YORK (Reuters) -Sanofi has reached an agreement in principle to settle 4,000 U.S. lawsuits linking the discontinued heartburn drug Zantac to cancer, the company said on Wednesday. Sanofi did ...

  7. Cimetidine - Wikipedia

    en.wikipedia.org/wiki/Cimetidine

    Subsequent to the introduction onto the U.S. drug market, two other H 2 receptor antagonists were approved, ranitidine (Zantac, Glaxo Labs) and famotidine (Pepcid, Yamanouchi, Ltd.) Cimetidine became the first drug ever to reach more than $1 billion a year in sales, thus making it the first blockbuster drug. [citation needed]

  8. GSK settles another Zantac lawsuit in California - AOL

    www.aol.com/news/gsk-confidentially-settles...

    The U.S. Food and Drug Administration (FDA) in 2020 pulled Zantac and its generic versions off the market, triggering a wave of lawsuits. GSK settles another Zantac lawsuit in California Skip to ...

  9. Zantac - Wikipedia

    en.wikipedia.org/wiki/Zantac

    Zantac can refer to either of two different H 2 antagonists used to reduce gastric acid secretion: Ranitidine , prior to its 2020 withdrawal from the market Famotidine , following the withdrawal of ranitidine

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