Ad
related to: how als affects the body function pdf free handout
Search results
Results from the WOW.Com Content Network
ALS is a motor neuron disease, which is a group of neurological disorders that selectively affect motor neurons, the cells that control voluntary muscles of the body. [3] Other motor neuron diseases include primary lateral sclerosis (PLS), progressive muscular atrophy (PMA), progressive bulbar palsy , pseudobulbar palsy , and monomelic ...
A score of 0 on a question would indicate no function while a score of 4 would indicate full function. [4] [5] This scale has been useful for doctors in diagnosing patients, measuring disease progression and also for researchers when selecting patients for a study and measuring the potential effects of a clinical trial. [4] [6]
Those that affect children tend to be inherited or familial, and their symptoms are either present at birth or appear before learning to walk. Those that affect adults tend to appear after age 40. [2] The clinical course depends on the specific disease, but most progress or worsen over the course of months. [6]
For premium support please call: 800-290-4726 more ways to reach us
A study introduced the SOD1/GFP transgenic zebra-fish to study that specific gene on the development and occurrence of ALS in the fish, and how can that be used in testing potential therapeutic molecules. [7] All the previous models are considered simple, and save time and money due to their short lifespan and small and simple body structure. [4]
PMA affects only the lower motor neurons, in contrast to amyotrophic lateral sclerosis (ALS), the most common MND, which affects both the upper and lower motor neurons, or primary lateral sclerosis, another MND, which affects only the upper motor neurons. The distinction is important because PMA is associated with a better prognosis than ALS.
Articles relating to amyotrophic lateral sclerosis (ALS), also known as motor neurone disease (MND) or Lou Gehrig's disease. It is a specific disease which causes the death of neurons controlling voluntary muscles. ALS is characterized by stiff muscles, muscle twitching, and gradually worsening weakness due to muscles decreasing in size.
The institute has raised and spent more than $100 million on research into effective treatments for ALS and practices open-source science. [19] After the discovery that the multiple sclerosis drug Gilenya might also be a treatment for ALS, the Institute enrolled 30 people in a Phase 2A clinical trial the drug in 2013, though it did not progress further.
Ad
related to: how als affects the body function pdf free handout