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Failure to use the correct equivalent amount can precipitate a severe withdrawal reaction. [119] Benzodiazepines with a half-life of more than 24 hours include chlordiazepoxide, diazepam, clobazam, clonazepam, chlorazepinic acid, ketazolam, medazepam, nordazepam, and prazepam.
The prosuicidal effects of benzodiazepines are suspected to be due to a psychiatric disturbance caused by side effects or withdrawal symptoms. [11] Because benzodiazepines in general may be associated with increased suicide risk, care should be taken when prescribing, especially to at-risk patients.
Physiological dependence was demonstrated by flumazenil-precipitated withdrawal. [77] Use of alcohol or other CNS depressants while taking clonazepam greatly intensifies the effects, including side effects, of the drug. A recurrence of symptoms of the underlying disease should be separated from withdrawal symptoms. [78]
However, these medications do not work for everyone and can cause unpleasant side effects for some patients. For those who have recovered with the aid of antidepressants, doctors and patients may ...
The elderly have less cognitive reserve and are more sensitive to the short (e.g., in between dose withdrawal) and protracted withdrawal effects of benzodiazepines, as well as the side-effects both from short-term and long-term use. This can lead to excessive contact with their doctor.
Some side effects, such as weight gain, occur more frequently with certain types of antidepressant medication. Switching to a new type of antidepressant may help reverse any weight gain you’ve ...
Clonazepam, known by its brand name Klonopin, is a popular drug that is used to treat some brain and mental disorders. ... the company warns of the possible side effects for specific patients ...
With most benzodiazepines, noticeable effects usually wear off within a few hours. Nevertheless, as long as the drug is present it will exert subtle effects within the body. These effects may become apparent during continued use or may appear as withdrawal symptoms when dosage is reduced or the drug is stopped. [citation needed]