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Haemophilia (British English), or hemophilia (American English) [6] (from Ancient Greek αἷμα (haîma) ' blood ' and φιλία (philía) ' love of '), [7] is a mostly inherited genetic disorder that impairs the body's ability to make blood clots, a process needed to stop bleeding.
"Hemophilia: The Royal Disease" Yelena Aronova-Tiuntseva and Clyde Freeman Herreid; Family tree of Queen Victoria and her descendants; Haemophilia in Queen Victoria's Descendants. Archived 2006-11-18 at the Wayback Machine; Victor A. McKusick (August 1965). "The Royal Hemophilia". Scientific American. pp. 88– 95
Contaminated hemophilia blood products were a serious public health problem in the late 1970s up to 1985. [citation needed] Hemophilia A causes a deficiency in Factor VIII, a protein required for blood clotting. Factor VIII injections are a common treatment to prevent or stop bleeding in people with hemophilia A. [1]
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Haemophilia is a mostly inherited genetic disorder that impairs the body's ability to clot, a process needed to stop bleeding. [20] [21] This results in people bleeding longer after an injury, easy bruising, and an increased risk of bleeding inside joints or other parts of the body.
Joint capsule. Haemophilia A's phenotype has a quite wide range of symptoms encompassing both internal and external bleeding episodes. Individuals with more severe haemophilia tend to experience more intense and frequent bleeding, whereas those with mild haemophilia typically exhibit milder symptoms unless subjected to surgical procedures or significant trauma.
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Haemophilia B, also spelled hemophilia B, is a blood clotting disorder causing easy bruising and bleeding due to an inherited mutation of the gene for factor IX, and resulting in a deficiency of factor IX. It is less common than factor VIII deficiency (haemophilia A). [3]
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