Search results
Results from the WOW.Com Content Network
A neoplasm (/ ˈ n iː oʊ p l æ z əm, ˈ n iː ə-/) [1] [2] is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists in growing abnormally, even if the original trigger is ...
The term also refers to a group of morphological changes in a cell (nuclear pleomorphism, altered nuclear-cytoplasmic ratio, presence of nucleoli, high proliferation index) that point to a possible malignant transformation. [1] Such loss of structural differentiation is especially seen in most, but not all, malignant neoplasms. [2]
Cancer is also euphemised as "the C-word"; [232] [233] [234] Macmillan Cancer Support uses the term to try to lessen the fear around the disease. [235] In Nigeria, one local name for cancer translates into English as "the disease that cannot be cured". [ 236 ]
The most common symptoms of CNS tumors are headache, vomiting, and nausea. Symptoms vary depending on the tumor and may include unsteady gait, slowed speech, memory loss, loss of hearing and vision, problems with memory, narrowing of visual field, and back pain. Symptoms may also vary greatly between individuals with the same tumor type.
While the telomeres of most cells shorten after each division, eventually causing the cell to die, telomerase extends the cell's telomeres. This is a major reason that cancer cells can accumulate over time, creating tumors. [39] A diagram illustrating the distinction between cancer stem cell targeted and conventional cancer therapies
The term dysplasia is typically used when the cellular abnormality is restricted to the originating tissue, as in the case of an early, in-situ neoplasm. [ citation needed ] Dysplasia, in which cell maturation and differentiation are delayed, can be contrasted with metaplasia , in which cells of one mature, differentiated type are replaced by ...
The accumulation of certain mutations over generations of somatic cells is part of the process of malignant transformation, from normal cell to cancer cell. Cells with heterozygous loss-of-function mutations (one good copy of a gene and one mutated copy) may function normally with the unmutated copy until the good copy has been spontaneously ...
Dysplasia is an abnormal type of excessive cell proliferation characterized by loss of normal tissue arrangement and cell structure in pre-malignant cells. These early neoplastic changes must be distinguished from hyperplasia , a reversible increase in cell division caused by an external stimulus, such as a hormonal imbalance or chronic irritation.