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The dural venous sinuses (also called dural sinuses, cerebral sinuses, or cranial sinuses) are venous sinuses (channels) found between the periosteal and meningeal layers of dura mater in the brain. [1] [2] They receive blood from the cerebral veins, and cerebrospinal fluid (CSF) from the subarachnoid space via arachnoid granulations.
The ventricular system is continuous with the central canal of the spinal cord from the fourth ventricle, [3] allowing for the flow of CSF to circulate. [ 3 ] [ 4 ] All of the ventricular system and the central canal of the spinal cord are lined with ependyma , a specialised form of epithelium connected by tight junctions that make up the blood ...
The leptomeningeal collateral circulation (also known as leptomeningeal anastomoses or pial collaterals) is a network of small blood vessels in the brain that connects branches of the middle, anterior and posterior cerebral arteries (MCA, ACA, and PCA), [1] with variation in its precise anatomy between individuals. [2]
Cerebral blood flow (CBF) is the blood supply to the brain in a given period of time. [8] In an adult, CBF is typically 750 millilitres per minute or 15.8 ± 5.7% of the cardiac output. [9] This equates to an average perfusion of 50 to 54 millilitres of blood per 100 grams of brain tissue per minute. [10] [11] [12]
The falx cerebri is a strong, crescent-shaped sheet of dura mater lying in the sagittal plane between the two cerebral hemispheres. [3] It is one of four dural partitions of the brain along with the falx cerebelli, tentorium cerebelli, and diaphragma sellae; it is formed through invagination of the dura mater into the longitudinal fissure between the cerebral hemispheres.
The blood–cerebrospinal fluid barrier (BCSFB) is a fluid–brain barrier that is composed of a pair of membranes that separate blood from CSF at the capillary level and CSF from brain tissue. [14] The blood–CSF boundary at the choroid plexus is a membrane composed of epithelial cells and tight junctions that link them. [ 14 ]
The dura mater covering the spinal cord is known as the dural sac or thecal sac, and only has one layer (the meningeal layer) unlike cranial dura mater. The potential space between these two layers is known as the epidural space , [ 5 ] which can accumulate blood in the case of traumatic laceration to the meningeal arteries .
Circumventricular organs (CVOs) (circum-: around ; ventricular: of ventricle) are structures in the brain characterized by their extensive and highly permeable capillaries, unlike those in the rest of the brain where there exists a blood–brain barrier (BBB) at the capillary level.