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The C-terminal telopeptide (CTX), also known as carboxy-terminal collagen crosslinks, is the C-terminal telopeptide of fibrillar collagens such as collagen type I and type II. It is used as a biomarker in the serum to measure the rate of bone turnover .
632 12095 Ensembl ENSG00000242252 ENSMUSG00000074489 UniProt P02818 P54615 RefSeq (mRNA) NM_199173 NM_031368 NM_001305448 NM_001305449 NM_001305450 RefSeq (protein) NP_954642 NP_001292377 NP_001292378 NP_001292379 NP_112736 Location (UCSC) Chr 1: 156.24 – 156.24 Mb Chr 3: 88.28 – 88.28 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Osteocalcin, also known as bone gamma ...
Laboratory Corporation of America Holdings (Labcorp), headquartered in Burlington, North Carolina, provides laboratory services used for diagnosis and healthcare decisions. [1] It operates one of the largest clinical laboratory networks in the world and has operations in over 100 countries; although its operations are primarily in the U.S. [ 1 ]
CTX is a three-letter abbreviation with multiple meanings: Medical. C-terminal telopeptide, a blood serum biomarker that can be measured to assess bone turnover;
CTX-M-15 (belonging to the CTX-M-1 cluster) is the most prevalent CTX-M-gene. [24] An example of beta-lactamase CTX-M-15, along with IS Ecp1 , has been found to have transposed onto the chromosome of Klebsiella pneumoniae ATCC BAA-2146. [ 25 ]
Beta-2 transferrin is a carbohydrate-free isoform of transferrin, which is almost exclusively found in the cerebrospinal fluid. It is not found in blood , mucus or tears , thus making it a specific marker of cerebrospinal fluid, applied as an assay in cases where cerebrospinal fluid leakage is suspected.
In a comparative study (in 2007), various detection kits had a sensitivity between 69.6% and 77.5% and a specificity between 87.8% and 96.4%. [12] Despite the excellent performance of these immunoassays, for example CCP-assays, they only provide a sensitivity comparable with that of rheumatoid factor (RF).
Multiplex ligation-dependent probe amplification was invented by Jan Schouten, a Dutch scientist. [1] The method was first described in 2002 in the scientific journal Nucleic Acid Research. [2]