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Metaplastic carcinoma, otherwise known as metaplastic breast cancer (MBC), is a heterogeneous group of cancers that exhibit varied patterns of metaplasia and differentiation along multiple cell lines.
The Mayo Clinic Cancer Center is one of the oldest NCI-designated cancer centers in the United States, having first been designated in 1973. [3] The main location of the Mayo Clinic is in Rochester, MN. Campuses in Arizona and Florida opened later and became part of the Mayo Clinic Cancer Center in 2003. [4] [5]
Staging breast cancer is the initial step to help physicians determine the most appropriate course of treatment. As of 2016, guidelines incorporated biologic factors, such as tumor grade, cellular proliferation rate, estrogen and progesterone receptor expression, human epidermal growth factor 2 (HER2) expression, and gene expression profiling into the staging system.
Mastectomy is the medical term for the surgical removal of one or both breasts, partially or completely.A mastectomy is usually carried out to treat breast cancer. [1] [2] In some cases, women believed to be at high risk of breast cancer choose to have the operation as a preventive measure. [1]
Proton beam therapy has been shown to be just as effective as traditional chemotherapy, with fewer side effects and less treatment time.
Metastatic breast cancer can be treated, sometimes for many years, but it cannot be cured. [2] Distant metastases are the cause of about 90% of deaths due to breast cancer. [3] Breast cancer can metastasize anywhere in body but primarily metastasizes to the bone, lungs, regional lymph nodes, liver and brain, with the most common site being the ...
Molecular classification of breast cancer from mRNA expression profiles. DNA microarrays have compared normal cells to breast cancer cells and found differences in the expression of hundreds of genes. Although the significance of many of those genetic differences is unknown, independent analyses by different research groups has found that ...
Breast-conserving surgery refers to an operation that aims to remove breast cancer while avoiding a mastectomy. [1] Different forms of this operation include: lumpectomy (tylectomy), wide local excision, segmental resection, and quadrantectomy. Breast-conserving surgery has been increasingly accepted as an alternative to mastectomy in specific ...
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