Search results
Results from the WOW.Com Content Network
Ototoxicity is the property of being toxic to the ear (oto-), specifically the cochlea or auditory nerve and sometimes the vestibular system, for example, as a side effect of a drug. The effects of ototoxicity can be reversible and temporary, or irreversible and permanent. It has been recognized since the 19th century. [1]
The results indicate the number of healthy years lost by a group of people over a specific time period. The National Institute for Occupational Safety and Health (NIOSH) used DALYs to estimate the impact of hearing loss on quality of life in the CDC Morbidity and Mortality Weekly Report article " Hearing Impairment Among Noise-Exposed Workers ...
A vestibular schwannoma (VS), also called acoustic neuroma, is a benign tumor that develops on the vestibulocochlear nerve that passes from the inner ear to the brain. The tumor originates when Schwann cells that form the insulating myelin sheath on the nerve malfunction.
Here's how to read an audiogram and a doctor's explanation of the most common results including sloping hearing loss, notched hearing loss, cookie-bite hearing loss and reverse-sloping hearing loss.
Otosclerosis results in an audiogram with significant loss at all frequencies, often of around 40 dB(HL). [12] A deficiency particularly around 2 kHz (termed a Carhart notch in the audiogram) is characteristic of either otosclerosis or a congenital ossicular anomaly. [13] Ménière's disease results in a severe loss at low frequencies. [14]
Long-term effects were also a concern, as patients were often cured and could expect long survival after chemotherapy. Infertility was a major long-term side effect, and even more seriously, the risk of developing treatment-related myelodysplasia or acute leukemia was increased up to 14-fold in patients who received MOPP. [14]
The results of pure-tone audiometry are however a very good indicator of hearing impairment. Hearing disability is defined by the WHO as a reduction in the ability to hear sounds in both quiet and noisy environments (compared to people with normal hearing), which is caused by a hearing impairment. [ 17 ]
GnRH agonists eventually cause the same side effects as orchiectomy but may cause worse symptoms at the beginning of treatment. When GnRH agonists are first used, testosterone surges can lead to increased bone pain from metastatic cancer, so antiandrogens or abarelix is often added to blunt these side effects.