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Bubonic plague 15–100 million 25–60% of European population [5] 541–549 North Africa, Europe, and Western Asia 3 HIV/AIDS pandemic: HIV/AIDS: 44 million (as of 2025) [a] 1981–present [6] Worldwide 4 Black Death: Bubonic plague: 25–50 million 30–60% of European population [7] 1346–1353 Europe, Asia, and North Africa 5 COVID-19 pandemic
Plague repeatedly struck the cities of North Africa. Algiers lost 30,000–50,000 inhabitants to it in 1620–1621, and again in 1654–1657, 1665, 1691, and 1740–1742. [178] Cairo suffered more than fifty plague epidemics within 150 years from the plague's first appearance, with the final outbreak of the second pandemic there in the 1840s. [115]
A COVID-19 vaccine is intended to provide acquired immunity against severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), the virus that causes coronavirus disease 2019 . Prior to the COVID-19 pandemic, an established body of knowledge existed about the structure and function of coronaviruses causing diseases like severe acute ...
Colorado health officials have confirmed a human case of the plague, the rare bacterial infection infamously known for killing tens of millions in 14th century Europe. Today, it's easily treated ...
The plague went on to eliminate a quarter to half the human population of the known world and was identified in 2013 as being caused by bubonic plague. [78] [79] Black Death (1331 to 1353): Also known as the Second Plague Pandemic. The total number of deaths worldwide is estimated at 75 to 200 million.
The director of the World Health Organization declared Friday that the coronavirus emergency was “over,” after three years of a world transformed by the COVID-19 pandemic, which killed at ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 17 December 2024. Disease caused by Yersinia pestis bacterium This article is about the disease caused by Yersinia pestis. For other uses, see Plague. Medical condition Plague Yersinia pestis seen at 200× magnification with a fluorescent label. Specialty Infectious disease Symptoms Fever, weakness ...
The bubonic plague was the most commonly seen form during the Black Death. The bubonic form of the plague has a mortality rate of thirty to seventy-five percent and symptoms include fever of 38–41 °C (101–105 °F), headaches, painful aching joints, nausea and vomiting, and a general feeling of malaise.