Search results
Results from the WOW.Com Content Network
I-Doser is an application for the playback of proprietary audio content. The developer claims the separately purchasable content aims to simulate specific mental states through the use of binaural beats, some of it is named after various recreational drugs. [1]
Download QR code; Print/export Download as PDF; Printable version ... C avg is the average concentration of a drug in the central circulation during a dosing interval ...
K i is the inhibition constant for a drug; the concentration of competing ligand in a competition assay which would occupy 50% of the receptors if no ligand were present. [ 5 ] The Cheng-Prusoff equation produces good estimates at high agonist concentrations, but over- or under-estimates K i at low agonist concentrations.
A common type of ab initio electronic structure calculation is the Hartree–Fock method (HF), an extension of molecular orbital theory, where electron-electron repulsions in the molecule are not specifically taken into account; only the electrons' average effect is included in the calculation. As the basis set size increases, the energy and ...
Another use is in the therapeutic drug monitoring of drugs with a narrow therapeutic index. For example, gentamicin is an antibiotic that can be nephrotoxic (kidney damaging) and ototoxic (hearing damaging); measurement of gentamicin through concentrations in a patient's plasma and calculation of the AUC is used to guide the dosage of this drug ...
For clarification, a graded dose response curve shows the graded effect of the drug (y axis) over the dose of the drug (x axis) in one or an average of subjects. A quantal dose response curve shows the percentage of subjects where a response is noted in an all-or-none manner (y axis) over the dose of the drug (x axis).
Get AOL Mail for FREE! Manage your email like never before with travel, photo & document views. Personalize your inbox with themes & tabs. You've Got Mail!
Drug design, often referred to as rational drug design or simply rational design, is the inventive process of finding new medications based on the knowledge of a biological target. [1] The drug is most commonly an organic small molecule that activates or inhibits the function of a biomolecule such as a protein , which in turn results in a ...