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In hypokalemic periodic paralysis, arginine residues making up the voltage sensor of Na v 1.4 are mutated. The voltage sensor comprises the S4 alpha helix of each of the four transmembrane domains (I-IV) of the protein, and contains basic residues that only allow entry of the positive sodium ions at appropriate membrane voltages by blocking or opening the channel pore.
In enzymology, a xyloglucan:xyloglucosyl transferase (EC 2.4.1.207) is an enzyme that catalyzes the chemical reaction in which a beta-(1,4) bond in the backbone of a xyloglucan in broken; the xyloglucanyl segment is then transferred to the O 4 of the non-reducing terminal glucose residue of either xyloglucan or an oligosaccharide thereof.
Brent crude, the international benchmark, rose 1.14% to $74.83 a barrel. Gold increased by 0.73% to $2,637.1 an ounce. The 10-year Treasury yield rose two basis points to 4.573%.
As New Year's Eve falls on a Tuesday, the stock market is open for regular trading hours, with the Nasdaq and the New York Stock Exchange operating from 9:30 a.m. to 4 p.m. EST.
The broad S&P 500 closed down 13 points, or 0.2%, after trading as low as 0.9% lower midday. The Dow Jones Industrial Average was down nearly half a percent at the close, while the Nasdaq ...
Thus, the two substrates of this enzyme are NDP-glucose and (1,4-alpha-D-glucosyl)n, whereas its two products are NDP and (1,4-alpha-D-glucosyl)n+1. This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is NDP-glucose:1,4-alpha-D-glucan 4-alpha-D ...
In enzymology, a 1,4-alpha-glucan 6-alpha-glucosyltransferase (EC 2.4.1.24) is an enzyme that catalyzes the chemical reaction that transfers an alpha-D-glucosyl residue in a 1,4-alpha-D-glucan to the primary hydroxyl group of glucose or 1,4-alpha-D-glucan. This enzyme belongs to the family of glycosyltransferases, specifically the ...
The top fundraising campaign on crowdfunding platform GoFundMe in 2024 reflects what has been a major pain point for millions of Americans: inflation. The company's annual giving report shows that ...