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  2. Myostatin inhibitor - Wikipedia

    en.wikipedia.org/wiki/Myostatin_inhibitor

    Androgens both regulate myostatin expression directly and upregulate follistatin expression. [3] YK-11, a selective androgen receptor modulator, is also a myostatin inhibitor. [4] [5] Resistance training reduces myostatin activity and increases follistatin activity. [6] Pharmacological myostatin inhibitors can therefore be considered exercise ...

  3. Stamulumab - Wikipedia

    en.wikipedia.org/wiki/Stamulumab

    Myostatin is a protein that inhibits the growth of muscle tissue, stamulumab is a recombinant human antibody designed to bind to and inhibit the activity of myostatin. [ 3 ] Stamulumab is a G1 immunoglobulin antibody which binds to myostatin and prevents it from binding to its target site, thus inhibiting the growth-limiting action of myostatin ...

  4. Apitegromab - Wikipedia

    en.wikipedia.org/wiki/Apitegromab

    Apitegromab (SRK-015) is a fully human monoclonal antibody developed to treat spinal muscular atrophy.It works by binding to and inhibiting promyostatin, a precursor to myostatin, which limits the size of skeletal muscle tissue, as well as inactive myostatin.

  5. Myostatin - Wikipedia

    en.wikipedia.org/wiki/Myostatin

    Myostatin (also known as growth differentiation factor 8, abbreviated GDF8) is a protein that in humans is encoded by the MSTN gene. [6] Myostatin is a myokine that is produced and released by myocytes and acts on muscle cells to inhibit muscle growth. [7] Myostatin is a secreted growth differentiation factor that is a member of the TGF beta ...

  6. Category:Myostatin inhibitors - Wikipedia

    en.wikipedia.org/wiki/Category:Myostatin_inhibitors

    Myostatin inhibitor; S. Stamulumab This page was last edited on 6 December 2023, at 05:05 (UTC). Text is available under the Creative Commons ...

  7. Exercise mimetic - Wikipedia

    en.wikipedia.org/wiki/Exercise_mimetic

    Myostatin myostatin inhibitors [ 6 ] The majority of the effect of exercise in reducing cardiovascular and all-cause mortality cannot be explained via improvements in quantifiable risk factors, such as blood cholesterol.

  8. YK-11 - Wikipedia

    en.wikipedia.org/wiki/YK-11

    YK-11 is a synthetic steroidal selective androgen receptor modulator (SARM). [1] [2] It is a gene-selective partial agonist of the androgen receptor (AR) and does not induce the physical interaction between the NTD/AF1 and LBD/AF2 (known as the N/C interaction), which is required for full transactivation of the AR.

  9. List of drugs banned by the World Anti-Doping Agency

    en.wikipedia.org/wiki/List_of_drugs_banned_by...

    Myostatin inhibitors are banned. Metabolic modulators including peroxisome proliferator-activated receptor delta (PPARδ) agonists (e.g., GW 1516), PPARδ-AMP-activated protein kinase (AMPK) axis agonists (e.g. AICAR) are also banned. Meldonium was banned on 1 January 2016, which was often used during the Russian doping scandal.

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