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Isoprenaline, also known as isoproterenol and sold under the brand name Isuprel among others, is a sympathomimetic medication which is used in the treatment of acute bradycardia (slow heart rate), heart block, and rarely for asthma, among other indications. [9]
The mechanisms of sympathomimetic drugs can be direct-acting (direct interaction between drug and receptor), such as α-adrenergic agonists, β-adrenergic agonists, and dopaminergic agonists; or indirect-acting (interaction not between drug and receptor), such as MAOIs, COMT inhibitors, release stimulants, and reuptake inhibitors that increase the levels of endogenous catecholamines.
Prior to their discovery, the non-selective beta-agonist isoprenaline was used. The aim of the drug development through the years has been to minimise side effects, achieve selectivity and longer duration of action. The mechanism of action is well understood and has facilitated the development.
When it comes to managing mild pain at home, there’s a strong probability you’ve already got a few types of OTC anti-inflammatories stocked in your medicine cabinet.
Dimethylallyl pyrophosphate, not isoprene itself, is the source of most terpenes.. Isoprene is produced and emitted by many species of trees (major producers are oaks, poplars, eucalyptus, and some legumes).
Clorprenaline (INN Tooltip International Nonproprietary Name, USAN Tooltip United States Adopted Name, BAN Tooltip British Approved Name), also known as isoprophenamine and known as clorprenaline hydrochloride (USAN Tooltip United States Adopted Name, JAN Tooltip Japanese Accepted Name) in the case of the hydrochloride salt, is a sympathomimetic and bronchodilator medication which is marketed ...
Dichloroisoprenaline (DCI), also known as dichloroisoproterenol, was the first beta blocker ever to be developed. It is non-selective for the β 1-adrenergic and β 2-adrenergic receptors.
Orciprenaline, also known as metaproterenol, is a bronchodilator used in the treatment of asthma. [1] [2] Orciprenaline is a moderately selective β 2 adrenergic receptor agonist that stimulates receptors of the smooth muscle in the lungs, uterus, and vasculature supplying skeletal muscle, with minimal or no effect on α adrenergic receptors.