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Ischemia or ischaemia is a restriction in blood supply to any tissue, muscle group, or organ of the body, causing a shortage of oxygen that is needed for cellular metabolism (to keep tissue alive). [ 3 ] [ 4 ] Ischemia is generally caused by problems with blood vessels , with resultant damage to or dysfunction of tissue i.e. hypoxia and ...
The process is the opposite of vasodilation, the widening of blood vessels. The process is particularly important in controlling hemorrhage and reducing acute blood loss. When blood vessels constrict, the flow of blood is restricted or decreased, thus retaining body heat or increasing vascular resistance.
Brain ischemia has been linked to a variety of diseases or abnormalities. Individuals with sickle cell anemia, compressed blood vessels, ventricular tachycardia, plaque buildup in the arteries, blood clots, extremely low blood pressure as a result of heart attack, and congenital heart defects have a higher predisposition to brain ischemia in comparison to the average population.
This increased pressure can cause tiny leg blood vessels to burst, even with minimal trauma (for example, sometimes even from aggressive scratching). This may cause tissue damage, and even lead to ...
If blood flow through the coronary arteries is stopped completely, cardiac muscle cells may die, known as a myocardial infarction, or heart attack. [9] Coronary artery disease (CAD) is the most common cause of coronary ischemia. [7] Coronary ischemia and coronary artery disease are contributors to the development of heart failure over time. [10]
Even in cases where there is a complete blockage to blood flow of a major blood vessel supplying the brain, there is typically some blood flow to the downstream tissue through collateral blood vessels, and the tissue can typically survive for some length of time that is dependent upon the level of remaining blood flow. [21] If blood flow is ...
Vascular dementia is dementia caused by a series of strokes. [2] [4] Restricted blood flow due to strokes reduces oxygen and glucose delivery to the brain, causing cell injury and neurological deficits in the affected region. [6]
An embolism involves the occlusion of blood vessels by an embolus. [1] Arterial occlusion by an embolus is termed 'arterial embolism'. An embolus is an agent that blocks blood flow by physically obstructing blood vessels. [1] This includes gas bubbles, [18] fatty deposits, amniotic fluid, [19] blood clots, and foreign material. Arterial emboli ...