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  2. Medicines and Related Substances Control Amendment Act, 1997

    en.wikipedia.org/wiki/Medicines_and_Related...

    South Africa's Medicines and Related Substance 1997 is a law enacted a compulsory license in order to fight HIV/AIDS epidemic. The intent of the Act was to reduce drug prices by allowing generic substitution of off-patent drugs, the parallel importation of on-patent drugs as well as price transparency.

  3. South African Health Products Regulatory Authority - Wikipedia

    en.wikipedia.org/wiki/South_African_Health...

    In January 2021, SAHPRA authorised under Section 21 of the Medicines and Related Substances Act, a Compassionate Use Access programme, which gave permission to five importers of unregistered Ivermectin in oral solid dosage form and for health facilities to hold bulk stock. The reasoning for this was to thwart the use of illicit and veterinary ...

  4. Medical experimentation in Africa - Wikipedia

    en.wikipedia.org/wiki/Medical_experimentation_in...

    The United States began testing AZT treatments in Africa in 1994, through projects funded by the Centers for Disease Control (CDC), the World Health Organization (WHO) and the National Institutes of Health (NIH). It included testing of over 17,000 women for a medication that prevents mother-to-child transmission of HIV/AIDS.

  5. Tolerability - Wikipedia

    en.wikipedia.org/wiki/Tolerability

    Tolerability, however, is often relative to the severity of the medical condition a drug is designed to treat. [1] For instance, cancer patients may tolerate significant pain or discomfort during a chemotherapeutic study with the hope of prolonging survival or finding a cure, whereas patients experiencing a benign condition, such as a headache ...

  6. Drug tolerance - Wikipedia

    en.wikipedia.org/wiki/Drug_tolerance

    Drug tolerance or drug insensitivity is a pharmacological concept describing subjects' reduced reaction to a drug following its repeated use. Increasing its dosage may re-amplify the drug's effects; however, this may accelerate tolerance, further reducing the drug's effects.

  7. List of acts of the Parliament of South Africa, 2020–2029

    en.wikipedia.org/wiki/List_of_Acts_of_the...

    Act no. Short title 1: National Public Health Institute of South Africa Act, 2020: 2: Border Management Authority Act, 2020: 3: National Minimum Wage Amendment Act, 2020: 4: Division of Revenue Act, 2020: 6: Defence Amendment Act, 2020: 7: Appropriation Act, 2020: 8: Civil Union Amendment Act, 2020: 9: Science and Technology Laws Amendment Act ...

  8. Management of HIV/AIDS - Wikipedia

    en.wikipedia.org/wiki/Management_of_HIV/AIDS

    A one pill, once a day combination therapy has been introduced in South Africa for as little as $10 per patient per month. [78] One 2013 study estimated an overall cost savings to ART therapy in South Africa given reduced transmission. [79] In the United States, new on-patent regimens can cost up to $28,500 per patient, per year. [80] [81]

  9. Drug test - Wikipedia

    en.wikipedia.org/wiki/Drug_test

    Urine drug tests screen the urine for the presence of a parent drug or its metabolites. The level of drug or its metabolites is not predictive of when the drug was taken or how much the patient used. [19] Urine drug testing is an immunoassay based on the principle of competitive binding. Drugs which may be present in the urine specimen compete ...