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User's guide for a Dulcitone keyboard. A user guide, also commonly known as a user manual, is intended to assist users in using a particular product, service or application. It is usually written by a technician, product developer, or a company's customer service staff. Most user guides contain both a written guide and associated images.
LGR5 is highly conserved within the mammalian clade. Sequence analyses showed that the transmembrane regions and cysteine-flanked junction between TM1 and the extracellular domain were highly conserved in sea anemone (Anthopleura elegantissima), fly (Drosophila melanogaster), worm (Caenorhabditis elegans), snail (Lymnaea stagnalis), rat (Rattus rattus) and human (Homo sapiens). [7]
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