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Azithromycin is an acid-stable antibiotic, so it can be taken orally with no need of protection from gastric acids. It is readily absorbed, but absorption is greater on an empty stomach. Time to peak concentration (T max) in adults is 2.1 to 3.2 hours for oral dosage forms.
Antimicrobial spectrum. A simplified diagram showing common disease-causing bacteria and the antibiotics which act against them. The antimicrobial spectrum of an antibiotic means the range of microorganisms it can kill or inhibit. Antibiotics can be divided into broad-spectrum antibiotics, extended-spectrum antibiotics and narrow-spectrum ...
Azithromycin: Zithromax, Sumamed, Xithrone: Streptococcal infections, syphilis, upper respiratory tract infections, lower respiratory tract infections, mycoplasmal infections, Lyme disease: Nausea, vomiting, and diarrhea (especially at higher doses) Prolonged cardiac QT interval (especially erythromycin) Hearing loss (especially at higher doses ...
Azithromycin stands apart from other macrolide antibiotics because it is a weak inhibitor of CYP3A4, and does not significantly increase AUC value of co-administered drugs. [ 32 ] The difference in CYP3A4 inhibition by macrolides has clinical implications, for example, for patients who take statins , which are cholesterol-lowering drugs that ...
Azithromycin is the most common first-line treatment, but the commonly-used 1 gram single-dose azithromycin treatment can lead to the bacteria commonly developing resistance to azithromycin. [21] An alternative five-day treatment with azithromycin showed no development of antimicrobial resistance. [22]
Treatment options include oral azithromycin and topical tetracycline. [3] Azithromycin is preferred because it can be used as a single oral dose. [6] After scarring of the eyelid has occurred, surgery may be required to correct the position of the eyelashes and prevent blindness. [2] Globally, about 80 million people have an active infection. [4]
One such cocktail – hydroxychloroquine combined with a high dose of zinc (as a sulfate, 220 mg (50 mg elemental Zn) per day for five days, a zinc dose ~4 times higher than the reference daily intake level) [62] and an approved antibiotic, either azithromycin or doxycycline – began in May as a Phase IV trial in New York State. [64]
Clarithromycin, sold under the brand name Biaxin among others, is an antibiotic used to treat various bacterial infections. [ 3 ] This includes strep throat, pneumonia, skin infections, H. pylori infection, and Lyme disease, among others. [ 3 ]
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