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Cushing's syndrome is a collection of signs and symptoms due to prolonged exposure to glucocorticoids such as cortisol. [4] [9] [10] Signs and symptoms may include high blood pressure, abdominal obesity but with thin arms and legs, reddish stretch marks, a round red face due to facial plethora, [11] a fat lump between the shoulders, weak muscles, weak bones, acne, and fragile skin that heals ...
Reproductive diseases. Prostate disease * in dogs includes benign prostatic hyperplasia (BPH), prostatitis (infection of the prostate), cancer, and cysts and abscesses. BPH is the most common and is found in older intact (not neutered) dogs. Signs include blood in the urine and straining to urinate and defecate.
Acanthosis nigricans. Acanthosis nigricans is a medical sign characterised by brown-to-black, poorly defined, velvety hyperpigmentation of the skin. [1] It is usually found in body folds, [2] such as the posterior and lateral folds of the neck, the armpits, groin, navel, forehead and other areas. [1]
Hyperpigmentation can be diffuse or focal, affecting such areas as the face and the back of the hands. Melanin is produced by melanocytes at the lower layer of the epidermis. Melanin is a class of pigment responsible for producing color in the body in places such as the eyes, skin, and hair. The process of melanin synthesis (melanogenesis ...
Canine histiocytic diseases. Histiocytic diseases in dogs are a group of diseases in dogs which may involve the skin, and which can be difficult to differentiate from granulomatous, reactive inflammatory or lymphoproliferative diseases. The clinical presentation and behaviour as well as response to therapy vary greatly among the syndromes.
Ocular melanosis (OM) is a blue-gray and/or brown lesion of the conjunctiva that can be separated into benign conjunctival epithelial melanosis (BCEM) and primary acquired melanosis (PAM), of which the latter is considered a risk factor for uveal melanoma. [1] The disease is caused by an increase of melanocytes in the iris, choroid, and ...
Waardenburg syndrome is a group of rare genetic conditions characterised by at least some degree of congenital hearing loss and pigmentation deficiencies, which can include bright blue eyes (or one blue eye and one brown eye), a white forelock or patches of light skin. These basic features constitute type 2 of the condition; in type 1, there is ...
Melanism. Melanistic black eastern grey squirrel (Sciurus carolinensis) Melanistic guinea pigs (Cavia porcellus) are rare, and are used in rituals by Andean curanderos. [1] Melanism is the congenital excess of melanin in an organism resulting in dark pigment. Pseudomelanism, also called abundism, is another variant of pigmentation, identifiable ...