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CLL is a type of cancer that affects the bone marrow and blood, causing too many lymphocytes to be produced. It usually affects older people and has no symptoms in early stages, but can lead to infections, anemia, and bone marrow failure.
Richter's transformation (RT) is the conversion of chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) into a more aggressive disease, such as diffuse large B-cell lymphoma (DLBCL) or Hodgkin's lymphoma (HL). RT is rare, occurs in 1-10% of CLL/SLL cases, and has a poor prognosis.
Lymphocytosis is an increase in the number or proportion of lymphocytes in the blood, which can indicate infection, leukemia, lymphoma or other conditions. Learn about the types, causes and diagnosis of lymphocytosis from this Wikipedia article.
Leukemia is a group of blood cancers that produce abnormal blood cells and affect the bone marrow and immune system. Learn about the four main types of leukemia (acute and chronic lymphocytic and myeloid), their causes, symptoms, diagnosis, treatment, and prognosis.
Leukemoid reaction is a high white blood cell count due to stress or infection, not a blood cancer. Learn how to distinguish it from chronic myelogenous leukemia (CML) by testing for the Philadelphia chromosome or BCR/ABL gene.
Learn about the causes, symptoms, diagnosis, and treatment of acute lymphoblastic leukemia, a cancer of the lymphoid line of blood cells. Find out the prognosis, frequency, and history of this disease, as well as the difference between B-cell and T-cell types.
Hairy cell leukemia is a rare type of chronic lymphocytic leukemia with abnormal B lymphocytes. Learn about its signs, symptoms, causes, pathophysiology, diagnosis, treatment, and prognosis.
Monoclonal B-cell lymphocytosis (MBL) is a condition with increased blood levels of abnormal B-cells that share features with CLL/SLL or other lymphomas. MBL is a premalignant disorder that may progress to different types of lymphocyte malignancies depending on the MBL phenotype.