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Genetic theories of aging propose that aging is programmed within each individual's genes. According to this theory, genes dictate cellular longevity. Programmed cell death, or apoptosis, is determined by a "biological clock" via genetic information in the nucleus of the cell. Genes responsible for apoptosis provide an explanation for cell ...
In general, biological aging clocks and biomarkers of aging are expected to find many uses in biological research since age is a fundamental characteristic of most organisms. Accurate measures of biological age (biological aging clocks) could be useful for testing the validity of various theories of biological aging,
The somatic mutation theory of ageing states that accumulation of mutations in somatic cells is the primary cause of aging. A comparison of somatic mutation rate across several mammal species found that the total number of accumulated mutations at the end of lifespan was roughly equal across a broad range of lifespans. [ 16 ]
As women age, ovarian reserve -- which is defined as the quantity and the quality of the eggs remaining in the ovaries -- declines, and when all eggs are depleted, menopause starts and ...
Pages in category "Theories of biological ageing" The following 30 pages are in this category, out of 30 total. ... Rate of living theory of aging;
In 1968 it took the form and became known as the neuroendocrine theory of aging. [38] [39] [40] 1956 Denham Harman proposed the free-radical theory of aging and demonstrated that free radical reactions contribute to the degradation of biological systems. [41] The theory is based on the ideas of Rebeca Gerschman and her colleagues put forward in ...
Biological aging explained "Chronological age is what the calendar tells us," Elissa Epel, PhD, a professor in the department of psychiatry & behavioral sciences at the University of California ...
Circadian clock, a molecular mechanism that results in a circadian rhythm in a living organism; Circadian rhythm, biological process that displays an oscillation about 24 hours, such as the human sleep-wake cycle (the "body clock") Epigenetic clock, a set of DNA sites whose methylation levels can be used to measure aging throughout the body