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Malathion is an acetylcholinesterase inhibitor, a diverse family of chemicals.Upon uptake into the target organism, it binds irreversibly to the serine residue in the active catalytic site of the cholinesterase enzyme.
Isomalathion is an impurity found in some batches of malathion. Whereas the structure of malation is, generically, RSP(S)(OCH 3) 2, the connectivity of isomalathion is RSPO(SCH 3)(OCH 3). It arises by heating malathion. Being significantly more toxic to humans than malathion, it has resulted in human poisonings. [1]
Parathion, also called parathion-ethyl or diethyl parathion, is an organophosphate insecticide and acaricide.It was originally developed by IG Farben in the 1940s. It is highly toxic to non-target organisms, including humans, so its use has been banned or restricted in most countries.
Azinphos-methyl is a neurotoxin derived from nerve agents developed during World War II. [4] It was first registered in the US in 1959 as an insecticide and is also used as active ingredient in organophosphate (OP) pesticides. [6]
Dimethoate is a widely used organophosphate insecticide and acaricide.It was patented and introduced in the 1950s by American Cyanamid.Like other organophosphates, dimethoate is an acetylcholinesterase inhibitor which disables cholinesterase, an enzyme essential for central nervous system function.
Most POPs (including dieldrin) bioaccumulate in the fatty tissues of humans and other animals. The Stockholm Convention banned twelve POPs, nicknamed "the dirty dozen". These include aldicarb , toxaphene , chlordane and heptachlor , chlordimeform , chlorobenzilate , DBCP , DDT, " drins " (aldrin, dieldrin and endrin), EDB, HCH and lindane ...
Power.” (Oxygen) — Released in December 2021, this 90-minute documentary special, hosted by Troy Roberts, looks into the boat crash, the murders, the insurance fraud and more.
Humans can be exposed to chlorpyrifos by way of ingestion (e.g., residue on treated produce, drinking water), inhalation (especially of indoor air), or absorption (i.e., through the skin). However, compared to other organophosphates, chlorpyrifos degrades relatively quickly once released into the environment.