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The Pancoast tumor was first described by Hare in 1838 as a "tumor involving certain nerves". [2] It was not until 1924 that the tumor was described in further detail, when Henry Pancoast, a radiologist from Philadelphia, published an article in which he reported and studied many cases of apical chest tumors that all shared the same radiographic findings and associated clinical symptoms, such ...
Stroke could occur at any age, including in childhood, the risk of stroke increases exponentially from 30 years of age, and the cause varies by age. [35] Advanced age is one of the most significant stroke risk factors. 95% of strokes occur in people age 45 and older, and two-thirds of strokes occur in those over the age of 65.
Age in itself is one of the most important risk factors for developing cancer. Currently, 60% of newly diagnosed malignant tumors and 70% of cancer deaths occur in people aged 65 years or older. [2] Many cancers are linked to aging; these include breast, colorectal, prostate, pancreatic, lung, bladder and stomach cancers.
Close family members of those with lung cancer have around twice the risk of developing lung cancer as an average person, even after controlling for occupational exposure and smoking habits. [78] Genome-wide association studies have identified many gene variants associated with lung cancer risk, each of which contributes a small risk increase. [79]
This study was a retrospective, case-control study that compared smoking habits of 684 individuals with bronchogenic carcinoma to those without the condition. [12] The survey included questions about smoking: starting age, 20 year tobacco consumption, brands used; as well as inquires about exposure to hazardous agents in the workplace, alcohol use, and causes of death for family members.
However, this increases the risk of lung bleeding, particularly in patients with squamous cell carcinoma. Crizotinib shows benefit in a subset of non-small cell lung cancer that is characterized by the EML4-ALK fusion oncogene, [24] and is approved by the FDA. [25] EML4-ALK is found in some relatively young, never or light smokers with ...
Genetics can also play a role as a family history of lung cancer can contribute to an increased risk of developing the disease. [1] Furthermore, research has revealed specific chromosome regions associated with increased risks of developing lung cancer. [1] In general, DNA damage appears to be the primary underlying cause of cancer. [19]
Conditions that may increase risk of diving disorders, but are not necessarily absolute contraindications: Patent foramen ovale; Diabetes mellitus — No serious problems should be expected during dives due to hypoglycaemia in divers with well-controlled diabetes. Long-term complications of diabetes should be considered and may be a ...
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