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Laboratory information management software for mass spectrometry information management and data analysis. OpenChrom: Open source: Chromatography and mass spectrometry software that can be extended using plug-ins and can run on several operating systems (Microsoft Windows, Linux, Unix, Mac OS X) and processor architectures (x86, x86_64, ppc).
While the first generation of MALDESI system was coupled to Fourier transform (FT) ion cyclotron resonance mass spectrometer, [3] the current source is interfaced with a Thermo Exploris 240 or a Q Exactive Plus mass spectrometer equipped with an Orbitrap mass analyzer. These mass analyzers offer equally accurate mass measurements but generally ...
The term matrix-assisted laser desorption ionization (MALDI) was coined in 1985 by Franz Hillenkamp, Michael Karas and their colleagues. [3] These researchers found that the amino acid alanine could be ionized more easily if it was mixed with the amino acid tryptophan and irradiated with a pulsed 266 nm laser.
A Bradbury–Nielsen shutter is a type of ion gate used in TOF mass spectrometers and in ion mobility spectrometers, as well as Hadamard transform TOF mass spectrometers. [9] The Bradbury–Nielsen shutter is ideal for fast timed ion selector (TIS)—a device used for isolating ions over narrow mass range in tandem (TOF/TOF) MALDI mass ...
MALDI mass spectrometry imaging (MALDI-MSI) is the use of matrix-assisted laser desorption ionization as a mass spectrometry imaging [2] technique in which the sample, often a thin tissue section, is moved in two dimensions while the mass spectrum is recorded. [3]
MS 2 – Mass spectrometry/mass spectrometry, i.e. tandem mass spectrometry; MS/MS – Mass spectrometry/mass spectrometry, i.e. tandem mass spectrometry; MALDESI – Matrix-assisted laser desorption electrospray ionization; MALDI – Matrix-assisted laser desorption/ionization; MAII – Matrix-assisted inlet ionization; MAIV – Matrix ...
In mass spectrometry, a matrix is a compound that promotes the formation of ions. Matrix compounds are used in matrix-assisted laser desorption/ionization (MALDI), matrix-assisted ionization (MAI), and fast atom bombardment (FAB).
A reflectron (mass reflectron) is a type of time-of-flight mass spectrometer (TOF MS) that comprises a pulsed ion source, field-free region, ion mirror, and ion detector and uses a static or time dependent electric field in the ion mirror to reverse the direction of travel of the ions entering it.