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Anthracimycin is a polyketide antibiotic discovered in 2013. Anthracimycin is derived from marine actinobacteria. In preliminary laboratory research, it has shown activity against Bacillus anthracis, [1] the bacteria that causes anthrax, and against methicillin-resistant Staphylococcus aureus (MRSA). [2]
Obiltoxaximab, sold under the brand name Anthim among others, is a monoclonal antibody medication designed for the treatment of exposure to Bacillus anthracis spores (etiologic agent of anthrax). [6] [3] [7] The medication was developed by Elusys Therapeutics, Inc. [3] [8]
Raxibacumab [2] is a human monoclonal antibody intended for the prophylaxis and treatment of inhaled anthrax.Its efficacy has been proven in rabbits and monkeys. [3] In December 2012 raxibacumab was approved in the United States for the treatment of inhalational anthrax due to Bacillus anthracis in combination with appropriate antibacterial drugs, and for prophylaxis of inhalational anthrax ...
Anthrax is an infection caused by the bacterium Bacillus anthracis or Bacillus cereus biovar anthracis. [2] Infection typically occurs by contact with the skin, inhalation, or intestinal absorption. [9] Symptom onset occurs between one day and more than two months after the infection is contracted. [1]
Common side effects of oral antibiotics include diarrhea, resulting from disruption of the species composition in the intestinal flora, resulting, for example, in overgrowth of pathogenic bacteria, such as Clostridioides difficile. [48] Taking probiotics during the course of antibiotic treatment can help prevent antibiotic-associated diarrhea. [49]
B. anthracis endospores, in particular, are highly resilient, surviving extremes of temperature, low-nutrient environments, and harsh chemical treatment over decades or centuries. [citation needed] The endospore is a dehydrated cell with thick walls and additional layers that form inside the cell membrane.
Doxycycline is a broad-spectrum antibiotic of the tetracycline class used in the treatment of infections caused by bacteria and certain parasites. [1] It is used to treat bacterial pneumonia, acne, chlamydia infections, Lyme disease, cholera, typhus, and syphilis. [1] It is also used to prevent malaria.
Treatment Prevention Actinomyces israelii: Oral flora [48] Actinomycosis: [48] painful abscesses and cysts MRSA in the mouth, lungs, [49] [50] or gastrointestinal tract. [35] Prolonged penicillin G and drainage [48] Bacillus anthracis: Contact with cattle, sheep, goats and horses [51] Spores enter through inhalation or through abrasions [33]