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Fructosamines are compounds that result from glycation reactions between glucose and a primary amine, followed by isomerization via the Amadori rearrangement.Biologically, fructosamines are recognized by fructosamine-3-kinase, which may trigger the degradation of advanced glycation end-products (though the true clinical significance of this pathway is unclear).
64122 63828 Ensembl ENSG00000167363 ENSMUSG00000025175 UniProt Q9H479 Q9ER35 RefSeq (mRNA) NM_022158 NM_001038699 NM_022014 RefSeq (protein) NP_071441 NP_001033788 NP_071297 Location (UCSC) Chr 17: 82.74 – 82.75 Mb Chr 11: 121.33 – 121.34 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Fructosamine-3-kinase is an enzyme that in humans is encoded by the FN3K gene. Function FN3K ...
Protein-fructosamine 3-kinase (EC 2.7.1.171, FN3K, fructosamine 3-kinase) is an enzyme with systematic name ATP:(protein)-N 6-D-fructosyl-L-lysine 3-phosphotransferase.
In molecular biology the fructosamine kinase family is a family of enzymes.This family includes eukaryotic fructosamine-3-kinase enzymes which may initiate a process leading to the deglycation of fructoselysine and of glycated proteins and in the phosphorylation of 1-deoxy-1-morpholinofructose, fructoselysine, fructoseglycine, fructose and glycated lysozyme. [1]
As the formation of glucosamine-6-phosphate is the first step for the synthesis of these products, glucosamine may be important in regulating their production; however, the way that the hexosamine biosynthesis pathway is actually regulated, and whether this could be involved in contributing to human disease remains unclear. [17]
Chemical structure of α-D-glucosamine.Note amine group (NH 2). Glucose.Note hydroxy group (OH) in place of the amine.. Hexosamines are amino sugars created by adding an amine group to a hexose.
Fructose malabsorption, formerly named dietary fructose intolerance (DFI), is a digestive disorder [1] in which absorption of fructose is impaired by deficient fructose carriers in the small intestine's enterocytes.
Blood glucose monitoring is the use of a glucose meter for testing the concentration of glucose in the blood ().Particularly important in diabetes management, a blood glucose test is typically performed by piercing the skin (typically, via fingerstick) to draw blood, then applying the blood to a chemically active disposable 'test-strip'.