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Danicopan, sold under the brand name Voydeya, is a medication used for the treatment of paroxysmal nocturnal hemoglobinuria. It is a complement inhibitor which reversibly binds to factor D to prevent alternative pathway-mediated hemolysis and deposition of complement C3 proteins on red blood cells. The most common side effects include fever, headache, increased levels of liver enzymes (a sign ...
Nocturnal polyuria is defined as an increase in urine production during the night but with a proportional decrease in daytime urine production that results in a normal 24-hour urine volume. With the 24-hour urine production within normal limits, nocturnal polyuria can be translated to having a nocturnal polyuria index (NPi) greater than 35% of ...
Hematuria or haematuria is defined as the presence of blood or red blood cells in the urine. [1] "Gross hematuria" occurs when urine appears red, brown, or tea-colored due to the presence of blood. Hematuria may also be subtle and only detectable with a microscope or laboratory test. [2]
Under ideal situations myoglobin will be filtered and excreted with the urine, but if too much myoglobin is released into the circulation or in case of kidney problems, it can occlude the kidneys' filtration system leading to acute tubular necrosis and acute kidney injury. Other causes of myoglobinuria include: McArdle's disease
In some cases, foamy urine may be a sign of kidney issues, diabetes, or even blood cancer. However, it could also be something entirely simple, like how the urine hits the surface of the toilet or ...
Chyluria, also called chylous urine, is a medical condition involving the presence of chyle in the urine stream, [1] which results in urine appearing milky white. [2] The condition is usually classified as being either parasitic or non parasitic. It is a condition that is more prevalent among people of Africa and the Indian subcontinent.
Good sleep is crucial for your overall health, but new research suggests it could impact your dementia risk, too. That’s the major takeaway from a November 2024 study published in the journal ...
But sundowning has some unique signs that make it stand out from just being tired. “Fatigue can occur at all times of the day. Sundowning is truly confusion,” Dr. Kobylarz says. “If you have ...