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  2. Shifts in brain activity may signal Alzheimer's long before ...

    www.aol.com/shifts-brain-activity-may-signal...

    The study found that increased levels of both amyloid-beta and tau proteins in the brain may lead to changed brain activity before the cognitive symptoms of Alzheimer’s disease appear. Focusing ...

  3. Amyloid plaques - Wikipedia

    en.wikipedia.org/wiki/Amyloid_plaques

    Some plaques occur in the brain as a result of aging, but large numbers of plaques and neurofibrillary tangles are characteristic features of Alzheimer's disease. [5] The plaques are highly variable in shape and size; in tissue sections immunostained for Aβ, they comprise a log-normal size distribution curve, with an average plaque area of 400 ...

  4. New test may detect Alzheimer's years before tau clumps ... - AOL

    www.aol.com/test-may-detect-alzheimers-years...

    Amyloid-beta: As Alzheimer’s disease develops, amyloid precursor proteins clump together to create amyloid-beta plaques, which eventually disrupt how brain cells work. Tau: In the healthy brain ...

  5. Alzheimer's disease - Wikipedia

    en.wikipedia.org/wiki/Alzheimer's

    The causes of Alzheimer's disease remain poorly understood. [16] There are many environmental and genetic risk factors associated with its development. The strongest genetic risk factor is from an allele of apolipoprotein E. [17] [18] Other risk factors include a history of head injury, clinical depression, and high blood pressure. [1]

  6. Biomarkers of Alzheimer's disease - Wikipedia

    en.wikipedia.org/wiki/Biomarkers_of_Alzheimer's...

    The biomarkers can be used to diagnose Alzheimer's disease (AD) in a very early stage, but they also provide objective and reliable measures of disease progress. It is imperative to diagnose AD disease as soon as possible, because neuropathologic changes of AD precede the symptoms by years. [ 1 ]

  7. How Pitt researchers hope to stop Alzheimer's symptoms ... - AOL

    www.aol.com/pitt-researchers-hope-stop-alzheimer...

    Instead, prospective enrollees will undergo a brain imaging scan to detect the presence of amyloid plaques, or clumps of proteins that build up between neurons and are linked to Alzheimer’s disease.

  8. Amyloid-related imaging abnormalities - Wikipedia

    en.wikipedia.org/wiki/Amyloid-related_imaging...

    Amyloid-related imaging abnormalities (ARIA) are abnormal differences seen in magnetic resonance imaging of the brain in patients with Alzheimer's disease. ARIA is associated with anti-amyloid drugs, particularly human monoclonal antibodies such as aducanumab. [1] There are two types of ARIA: ARIA-E and ARIA-H.

  9. Study detects early Alzheimer's 'stealth' phase before ... - AOL

    www.aol.com/study-detects-early-alzheimers...

    Alzheimer’s disease has a long pre-symptomatic period; Alzheimer’s-related changes take place in the brain 10, 15, even 20 years before the onset of memory and thinking symptoms.

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