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Fluorescence guided surgery (FGS), also called fluorescence image-guided surgery, or in the specific case of tumor resection, fluorescence guided resection, is a medical imaging technique used to detect fluorescently labelled structures during surgery. [1]
Fluorescence image guided surgery: is a medical imaging approach that fluorescently labels a mass to aid in navigation. For example, indocyanine green can be used to detect lymph nodes in cancer patients.
Pafolacianine, sold under the brand name Cytalux, is an optical imaging agent used in fluorescence-guided surgery. [1] [2] [3] [4] [5] [6] Pafolacianine is a ...
As fluorescence is a special case of luminescence, digital X-ray imaging is conceptually similar to digital gamma ray imaging (scintigraphy, SPECT, and PET) in that in both of these imaging mode families, the information conveyed by the variable attenuation of invisible electromagnetic radiation as it passes through tissues with various ...
Two-photon excitation microscopy of mouse intestine.Red: actin.Green: cell nuclei.Blue: mucus of goblet cells.Obtained at 780 nm using a Ti-sapphire laser.. Two-photon excitation microscopy (TPEF or 2PEF) is a fluorescence imaging technique that is particularly well-suited to image scattering living tissue of up to about one millimeter in thickness.
Pegulicianine is indicated for fluorescence imaging in adults with breast cancer as an adjunct for the intraoperative detection of cancerous tissue within the resection cavity following removal of the primary specimen during lumpectomy surgery. [1] [2] [3]
When fluorescence modality is adopted to such devices, the technique is also called fluorescence image-guided surgery. Image-guided surgery using medical ultrasound utilises sounds waves and as such does not require the protection and safety precautions necessary with ionising radiation modalities such as fluoroscopy , CT, X-Ray and tomography.
She is known for her work pioneering fluorescence guided surgery and co-holds several patents with Nobel Laureate Roger Y. Tsien, PhD [2] pertaining to their invention of peptides, [3] imaging systems and methods to support fluorescence-guided cancer tumor resection and fluorescent labeling of nerves on the surgical bed. [4]