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Spindle cell lipoma is most frequently located in the upper back, shoulder, or posterior neck subcutaneous layer. [3] Nonetheless, reports of it occurring in the mediastinum, hypopharynx, larynx, anterior neck, suprasellar region, esophagus, nasal vestibule, tongue, floor of mouth, vallecula, parotid gland, and breast have been made. [4]
Spindle-cell hemangioendothelioma [3]) is a vascular tumor that was first described in 1986 by Sharon Weiss, M.D., [4] and commonly presents in a child or young adult who develops blue nodules of firm consistency on a distal extremity.
Furthermore, multinucleated large cells with radically positioned nuclei in a "floret-like" pattern are strewn among the spindle cells. The histological spectrum is rather diverse, ranging from a tumor that primarily consists of spindle cells with only a few fat cells to a tumor that resembles an average lipoma with few spindle cells ...
Microscopic histopathologic views of hematoxylin and eosin stained tumor tissue show whorled and bundled, uniform, bland-appearing, slender fibroblastic spindle-shaped cells with elongated, tapered nuclei. The cells have scant cytoplasm and do not appear to be rapidly proliferating as defined by their low rate of mitosis.
Atypical fibroxanthoma (AFX) is frequently found to have a well-circumscribed, nonencapsulated dermal tumor that is either contiguous with the epidermis or separated from it by a narrow zone of collagen (Grenz zone); plump spindle cells with prominent nuclei, epithelioid cells, and multinucleated giant cells; atypical mitoses and severe ...
Spindle cell sarcoma is a type of connective tissue cancer. The tumors generally begin in layers of connective tissue, as found under the skin, between muscles, and surrounding organs, and will generally start as a small, inflamed lump, which grows in size. At first, the lump is, small in size, as the tumor exists in stage 1, and will not ...
IMT lesions typically consist of, and are defined by, myofibrolastic spindle cells, [7] i.e. specialized cells that are longer than wide, have a microscopic appearance that merges the appearances of fibroblasts and smooth muscle cells (see myofibroblast), occur in normal as well as tumor tissues, and in normal tissues are commonly designated ...
Main histopathology features of squamous-cell carcinoma. Squamous-cell carcinoma (SCC), also known as epidermoid carcinoma, comprises a number of different types of cancer that begin in squamous cells. [1] These cells form on the surface of the skin, on the lining of hollow organs in the body, and on the lining of the respiratory and digestive ...