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Tetrahydrobiopterin (BH 4, THB), also known as sapropterin (), [5] [6] is a cofactor of the three aromatic amino acid hydroxylase enzymes, [7] used in the degradation of amino acid phenylalanine and in the biosynthesis of the neurotransmitters serotonin (5-hydroxytryptamine, 5-HT), melatonin, dopamine, norepinephrine (noradrenaline), epinephrine (adrenaline), and is a cofactor for the ...
Tetrahydrobiopterin deficiency (THBD, BH 4 D) is a rare metabolic disorder that increases the blood levels of phenylalanine.Phenylalanine is an amino acid obtained normally through the diet, but can be harmful if excess levels build up, causing intellectual disability and other serious health problems.
Established in 2002, the Canadian International Pharmacy Association ("CIPA") is a Canadian association of licensed pharmacy businesses offering mail order pharmacy services to Canadian and international patients. CIPA members sell pharmaceuticals and maintenance medications to individuals upon receipt of a valid prescription.
BH4 is the principal active cofactor. BH4 synthesis occurs through two principal pathways; the de novo pathway involves three enzymatic steps and proceeds from GTP, while the salvage pathway converts sepiapterin to BH4 using dihydrofolate reductase. [4] In addition, BH2 is recycled to BH4 by dihydrobiopterin reductase.
The current version of ShuntCheck was developed in 2011-2012 funded by grants from the National Institute of Health [17] [18] [19] and was cleared by the US FDA in 2013. [1] ...
Ball-and-stick model of the tetrahydroborate anion, [BH 4] −. Borohydride refers to the anion [B H 4] −, which is also called tetrahydridoborate, and its salts. [1] Borohydride or hydroborate is also the term used for compounds containing [BH 4−n X n] −, where n is an integer from 0 to 3, for example cyanoborohydride or cyanotrihydroborate [BH 3 (CN)] − and triethylborohydride or ...
Pharmasave's national office is located in Langley, British Columbia.Its stores are located in nine provinces and territories across Canada and are organized into 2 regions with each region having their own regional offices: West (British Columbia, Alberta, Saskatchewan, Manitoba, and Yukon), and East (Ontario, Newfoundland and Labrador, New Brunswick, Nova Scotia, and Prince Edward Island).
Technetium 99m Tc albumin aggregated (99m Tc-MAA) is an injectable radiopharmaceutical used in nuclear medicine.It consists of a sterile aqueous suspension of Technetium-99m (99m Tc) labeled to human albumin aggregate particles.