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Cannabinoids (/ k ə ˈ n æ b ə n ɔɪ d z ˌ ˈ k æ n ə b ə n ɔɪ d z /) are compounds found in the cannabis plant or synthetic compounds that can interact with the endocannabinoid system. [1] [2] The most notable cannabinoid is the phytocannabinoid tetrahydrocannabinol (THC) (Delta-9-THC), the primary intoxicating compound in cannabis.
Close up of a Cannabis plant. Cannabis (/ˈkænəbɪs/) is commonly known as marijuana or hemp and has two known strains: Cannabis sativa and Cannabis indica, both of which produce chemicals to deter herbivory. The chemical composition includes specialized terpenes and cannabinoids, mainly tetrahydrocannabinol (THC), and cannabidiol (CBD ...
The Δ 9 isomer of THCP occurs naturally in cannabis, but in small amounts.A 2021 study reported the content of Δ 9-THCP ranging from 0.0023% to 0.0136% (w/w) (approximately 0.02–0.13 mg/g) without correlation to THC percentage in Δ 9-THC-dominant strains of cannabis; that study failed to detect THCP in CBD-dominant strains.
CBD shares a precursor with THC and is the main cannabinoid in CBD-dominant Cannabis strains. CBD has been shown to play a role in preventing the short-term memory loss associated with THC. [29] There is tentative evidence that CBD has an anti-psychotic effect, but research in this area is limited. [30] [24]
Sinsemilla cannabis is a cultivation technique, so it should not be confused with skunk, which refers to strains with a high percentage of THC, of up to 34% THC content. [6] The expression sinsemilla is practically obsolete since feminized seeds emerged in the 1990s, seeds genetically modified to only sprout females.
The two species of the Cannabis genus that are most commonly grown are Cannabis indica and Cannabis sativa. [5] A third species, Cannabis ruderalis, is very short and produces only trace amounts of tetrahydrocannabinol (THC), and thus is not commonly grown for industrial, recreational or medicinal use.
Both hops and cannabis contain terpenes and terpenoids; tetrahydrocannabinol (THC) is a terpenoid. [ 3 ] [ 4 ] Hops lack the enzyme that could convert cannabigerolic acid into THC or CBD, [ 5 ] but it could be inserted using genetic engineering as was done in 2019 for yeast.
Δ 9-Tetrahydrocannabutol (tetrahydrocannabinol-C4, THC-C4, Δ 9-THCB, (C4)-Δ 9-THC, butyl-THC) is a phytocannabinoid found in cannabis that is a homologue of tetrahydrocannabinol (THC), the main active component of Cannabis. [1] Structurally, they are only different by the pentyl side chain being replaced by a butyl side chain.
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