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Funnel plots, introduced by Light and Pillemer in 1984 [1] and discussed in detail by Matthias Egger and colleagues, [2] [3] are useful adjuncts to meta-analyses. A funnel plot is a scatterplot of treatment effect against a measure of study precision.
The p-value was first formally introduced by Karl Pearson, in his Pearson's chi-squared test, [39] using the chi-squared distribution and notated as capital P. [39] The p-values for the chi-squared distribution (for various values of χ 2 and degrees of freedom), now notated as P, were calculated in (Elderton 1902), collected in (Pearson 1914 ...
Pearson's chi-squared test or Pearson's test is a statistical test applied to sets of categorical data to evaluate how likely it is that any observed difference between the sets arose by chance. It is the most widely used of many chi-squared tests (e.g., Yates , likelihood ratio , portmanteau test in time series , etc.) – statistical ...
The interpretation of a p-value is dependent upon stopping rule and definition of multiple comparison. The former often changes during the course of a study and the latter is unavoidably ambiguous. (i.e. "p values depend on both the (data) observed and on the other possible (data) that might have been observed but weren't"). [68]
There are two versions of the technique: (i) direct interpretation of the HMP as an approximate p-value and (ii) a procedure for transforming the HMP into an asymptotically exact p-value. The approach provides a multilevel test procedure in which the smallest groups of p-values that are statistically significant may be sought.
The p-value for the permutation test is the proportion of the r values generated in step (2) that are larger than the Pearson correlation coefficient that was calculated from the original data. Here "larger" can mean either that the value is larger in magnitude, or larger in signed value, depending on whether a two-sided or one-sided test is ...
A two-tailed test applied to the normal distribution. A one-tailed test, showing the p-value as the size of one tail. In statistical significance testing, a one-tailed test and a two-tailed test are alternative ways of computing the statistical significance of a parameter inferred from a data set, in terms of a test statistic. A two-tailed test ...
Under Fisher's method, two small p-values P 1 and P 2 combine to form a smaller p-value.The darkest boundary defines the region where the meta-analysis p-value is below 0.05.. For example, if both p-values are around 0.10, or if one is around 0.04 and one is around 0.25, the meta-analysis p-value is around 0