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Eric A. Johnson is a microbiologist and an academic.He is a retired Professor of Bacteriology from the University of Wisconsin-Madison, serving from 1985 to 2020. [1]Johnson, most known for his research on Clostridium botulinum and its neurotoxins in food and industrial microbiology, has developed physiochemical-based methods for basic and applied research of Clostridium botulinum and ...
Astaxanthin is used as a dietary supplement for human, animal, and aquaculture consumption. [3] Astaxanthin from algae, synthetic and bacterial sources is generally recognized as safe in the United States. [11] The US Food and Drug Administration has approved astaxanthin as a food coloring (or color additive) for specific uses in animal and ...
6-Diazo-5-oxo-L-norleucine (DON) is a glutamine antagonist, which was isolated originally from Streptomyces in a sample of Peruvian soil.This diazo compound is biosynthesized from lysine by three enzymes in bacteria. [2]
Cancer research is research into cancer to identify causes and develop strategies for prevention, diagnosis, treatment, and cure. Cancer research ranges from epidemiology, molecular bioscience to the performance of clinical trials to evaluate and compare applications of the various cancer treatments.
Astaxanthin – Anthocyanins: 8.5 fold improvement in pharmacokinetics over the complex-free anthocyanins Lycopene – 50 mg phosphatidylcholine: improvement of lycopene pharmacokinetics by 8 fold in patients with coronary heart disease [ 46 ]
Due to the nature of canthaxanthin, relative to astaxanthin (a carotenoid of significant commercial value) these beta-carotene ketolase proteins have been studied extensively. [ 16 ] [ 17 ] An E. coli based production system has been developed, that achieved canthanaxanthin production at 170 mg/L in lab scale fermentation.
Crocin has also shown antiproliferative action against cancer cells in vitro. [18] [19] [20] and in vivo. [21] Crocin through the PI3K/AKT/mTOR, MAPK, VEGF, Wnt/β-catenin, and JAK-STAT suppression has antiproliferative properties. Also, the Nrf2 and p53 signaling pathway activation may be effective in the antiproliferative effect of crocin. [22]
At the Institute of Vision Research, Waterford Institute of Technology, the Meso-zeaxanthin Ocular Supplementation Trials (MOST), have been conducted to evaluate safety, MP response, and serum carotenoid response in subjects with and without AMD, following consumption of a supplement containing all three macular carotenoids in which meso ...
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