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  2. Thalidomide scandal - Wikipedia

    en.wikipedia.org/wiki/Thalidomide_scandal

    Feet of a baby born to a mother who had taken thalidomide while pregnant. In the late 1950s and early 1960s, the use of thalidomide in 46 countries was prescribed to women who were pregnant or who subsequently became pregnant, and consequently resulted in the "biggest anthropogenic medical disaster ever," with more than 10,000 children born with a range of severe deformities, such as ...

  3. Terry Wiles - Wikipedia

    en.wikipedia.org/wiki/Terry_Wiles

    Len and Terry Wiles c. 1970. Terrence 'Terry' Wiles (born 12 January 1962) was one of the most visible thalidomide babies born in the United Kingdom. He has since become known internationally through the Emmy Award winning [1] [2] television drama On Giant's Shoulders and the best-selling book of the same name.

  4. A Private Matter - Wikipedia

    en.wikipedia.org/wiki/A_Private_Matter

    A Private Matter is a 1992 American made-for-television drama film based on the true 1962 story of Sherri Finkbine, a resident of Phoenix, Arizona in the first trimester of her fifth pregnancy. She was the popular hostess of the locally produced children's television show Romper Room .

  5. Frances Oldham Kelsey - Wikipedia

    en.wikipedia.org/wiki/Frances_Oldham_Kelsey

    Frances Kathleen Oldham Kelsey CM (née Oldham; July 24, 1914 – August 7, 2015) was a Canadian-American [1] pharmacologist and physician. As a reviewer for the U.S. Food and Drug Administration (FDA), she refused to authorize thalidomide for market because she had concerns about the lack of evidence regarding the drug's safety. [2]

  6. On Giant's Shoulders - Wikipedia

    en.wikipedia.org/wiki/On_Giant's_Shoulders

    On Giant's Shoulders is a 1979 BBC television film about the early life of thalidomide victim Terry Wiles, with Wiles playing himself. The drama also starred Bryan Pringle and Judi Dench and won an Emmy Award in 1980. [1] [2]

  7. Sherri Chessen - Wikipedia

    en.wikipedia.org/wiki/Sherri_Chessen

    Sherri Chessen (born 1932), also known as Sherri Finkbine, is an American former children's television host.She is also known as Miss Sherri, her role on the Phoenix version of the franchised children's show Romper Room.

  8. William McBride (doctor) - Wikipedia

    en.wikipedia.org/wiki/William_McBride_(doctor)

    McBride published a letter in The Lancet, in December 1961, noting a large number of birth defects in children of patients who were prescribed thalidomide, [9] after a midwife named Sister Pat Sparrow first suspected the drug was causing birth defects in the babies of patients under his care at Crown Street Women's Hospital in Sydney. [10]

  9. Thalidomide - Wikipedia

    en.wikipedia.org/wiki/Thalidomide

    Thalidomide is racemic; while S-thalidomide is the bioactive form of the molecule, the individual enantiomers can racemize to each other due to the acidic hydrogen at the chiral centre, which is the carbon of the glutarimide ring bonded to the phthalimide substituent. The racemization process can occur in vivo.

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