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Density: 0.742 g mL −1: Melting point: −50 to −46 °C (−58 to −51 °F; 223 to 227 K) ... N,N-Diisopropylethylamine, or Hünig's base, is an organic compound ...
It is also used to prepare N,N-diisopropylethylamine (Hünig's base) by alkylation with diethyl sulfate. [8] The bromide salt of diisopropylamine, diisopropylammonium bromide, is a room-temperature organic ferroelectric material. [9]
The molecular formula C 8 H 19 N (molar mass: ... N,N-Diisopropylethylamine, or Hünig's base; Octodrine; Oenethyl This page was last edited on 17 January 2025, at 01 ...
A variety of amines and nitrogen heterocycles are useful bases of moderate strength (pK a of conjugate acid around 10-13) . N,N-Diisopropylethylamine (DIPEA, also called Hünig's Base [1]), pK a = 10.75
N,N-Diisopropylaminoethanol (DIPA) is a processor for production of various chemicals and also an intermediate in the production of the nerve agents VX and NX. [ 2 ] It is a colorless liquid, although aged samples can appear yellow.
Another non-nucleophilic base is N,N-diisopropylethylamine. Its aqueous p K aH (conjugate acid dissociation constant, a measure of basicity) is 11.07 at 25 °C, [ 1 ] while its p K a (acid dissociation constant, a measure of acidity) is approximately 37.
HATU was first reported by Louis A. Carpino in 1993 as an efficient means of preparing active esters derived from 1-hydroxy-7-azabenzotriazole (HOAt). [2] HATU is commonly prepared from HOAt and TCFH under basic conditions [3] and can exist as either the uronium salt (O-form) or the less reactive iminium salt (N-form).
Isopropylamine can be obtained by reaction of isopropyl alcohol with ammonia in presence of a catalyst: [3] (CH 3) 2 CHOH + NH 3 → (CH 3) 2 CHNH 2 + H 2 O. Isopropylamine is a building block for the preparation of many herbicides and pesticides including atrazine, bentazon, glyphosate, imazapyr, ametryne, desmetryn, prometryn, pramitol, dipropetryn, propazine, fenamiphos, and iprodione. [3]