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The elusive nature of primary hypertension and the precise mechanisms underlying an elevation of blood pressure (BP), even in cases of secondary hypertension and in models of experimental hypertension, have remained a focus of debate and research for more than a century.
A Mayo Clinic expert explains. Learn more about hypertension from nephrologist Leslie Thomas, M.D. Show Transcript. High blood pressure is a common condition that affects the body's arteries. It's also called hypertension. If you have high blood pressure, the force of the blood pushing against the artery walls is consistently too high.
Summarize the pathophysiology of essential hypertension and its pathological sequelae on organ systems throughout the body. Review the various treatment options for treating essential hypertension, both pharmacological as well as lifestyle modification strategies.
The pathogenesis of essential hypertension (primary hypertension, idiopathic hypertension) is multifactorial and highly complex, often involving reciprocal influences between different...
Pathophysiology. Hypertension is a chronic elevation of blood pressure that, in the long-term, causes end-organ damage and results in increased morbidity and mortality. Blood pressure is the product of cardiac output and systemic vascular resistance.
This Primer will discuss the epidemiology and pathophysiology of primary hypertension, prevention strategies for slowing the progression of BP elevation, management strategies (including optimal BP targets) for lowering BP and preventing CVD outcomes in patients with established hypertension and the effects of antihypertensive treatment on ...
Pathophysiology |. Symptoms and Signs |. Diagnosis |. Treatment |. Prognosis |. Key Points |. More Information. Hypertension is sustained elevation of resting systolic blood pressure (≥ 130 mm Hg), diastolic blood pressure (≥ 80 mm Hg), or both. Hypertension with no known cause (primary; formerly, essential, hypertension) is most common.
Hypertension is caused by increased cardiac output and/or increased peripheral resistance. Areas covered: The various mechanisms affecting cardiac output/peripheral resistance involved in the development of essential hypertension are covered.
The pathophysiology of hypertension is an area which attempts to explain mechanistically the causes of hypertension, which is a chronic disease characterized by elevation of blood pressure. Hypertension can be classified by cause as either essential (also known as primary or idiopathic) or secondary.
Pathophysiology of Hypertension. The Mosaic Theory and Beyond. David G. Harrison , Thomas M. Coffman, Christopher S. Wilcox. ABSTRACT: Dr Irvine Page proposed the Mosaic Theory of Hypertension in the 1940s advocating that hypertension is the result of many factors that interact to raise blood pressure and cause end-organ damage.