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According to Henn et al. 2009, phylogeny based methods take into account events that occur over long time scales and are thus less affected by stochastic fluctuations. Howell et al. 2003 suggests that selection, saturation, parallel mutations and genetic drift are responsible for the differences observed between pedigree based methods and ...
Lead Time vs Turnaround Time: Lead Time is the amount of time, defined by the supplier or service provider, that is required to meet a customer request or demand. [5] Lead-time is basically the time gap between the order placed by the customer and the time when the customer get the final delivery, on the other hand the Turnaround Time is in order to get a job done and deliver the output, once ...
Biology is a quarterly, peer-reviewed, open access, scientific journal covering research on all aspects of biology. It was established in 2012 and is published by MDPI. The editor-in-chief is Chris O'Callaghan (University of Oxford). The journal publishes reviews, research papers, and communications.
Journal of Bioinformatics and Computational Biology; Journal of Biomedical Informatics; Journal of Computational Biology; Journal of Mathematical Biology; Journal of Theoretical Biology; PLOS Computational Biology; Source Code for Biology and Medicine; Statistical Applications in Genetics and Molecular Biology; Statistics in Biosciences
The molecular clock is a figurative term for a technique that uses the mutation rate of biomolecules to deduce the time in prehistory when two or more life forms diverged.The biomolecular data used for such calculations are usually nucleotide sequences for DNA, RNA, or amino acid sequences for proteins.
The most accurate results can be obtained by use of "arrayed" functional genomics libraries, i.e. each library contains a single construct such as a single siRNA or cDNA. Functional genomics is typically paired with high content screening using e.g. epifluorescent microscopy or laser scanning cytometry.
Chronobiology comes from the ancient Greek χρόνος (chrónos, meaning "time"), and biology, which pertains to the study, or science, of life. The related terms chronomics and chronome have been used in some cases to describe either the molecular mechanisms involved in chronobiological phenomena or the more quantitative aspects of ...
Colocalization is used in real-time single-molecule fluorescence microscopy to detect interactions between fluorescently labeled molecular species. In this case, one species (e.g. a DNA molecule) is typically immobilized on the imaging surface, and the other species (e.g. a DNA-binding protein) is supplied to the solution.