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The symptoms of CmRD are similar to the physical symptoms of malnutrition, as the disease arises due to the poor absorption of lipids and fat-soluble nutrients such as vitamin E. For this reason, the disease is likely to be underdiagnosed by physicians. Fat-soluble nutrients are essential for growth, development, and normal bodily function.
It is essential that the blood-glucose levels remain at adequate levels to prevent the body from moving fat to the liver for energy. This involves snacking on low-fat, high-carbohydrate nutrients every 2–6 hours. However, some adults and children can sleep for 8–10 hours through the night without snacking. [1] [7]
The stool may contain large chunks of fat and/or blood. Infants often present with gastrointestinal problems caused by the poor fat absorption, which also contributes to steatorrhea. Other features of this disorder may develop later in childhood and often impair the function of the nervous system.
Breaking the cycle of malnutrition during early childhood development can break the cycle of intergenerational poverty among poor communities. [7] There are a variety of ways in which malnutrition can affect the body. Globally, 162 million children show symptoms of malnutrition such as stunting, which is an indicator of malnourishment. [7]
Small intestine : major site of absorption. Symptoms can manifest in a variety of ways and features might give a clue to the underlying condition. Symptoms can be intestinal or extra-intestinal - the former predominates in severe malabsorption. [citation needed] Diarrhoea, often steatorrhoea, is the most common feature. Watery, diurnal and ...
Organs often affected in children with kwashiorkor include the kidneys, pancreas, heart, and nervous system. [3] Other findings that may be encountered on physical exam include a distended abdomen, hair thinning, loss of teeth, skin or hair depigmentation, and dermatitis. Children with kwashiorkor often develop irritability and anorexia ...
Abetalipoproteinemia is a rare inherited disorder of fat metabolism that results in poor absorption of dietary fat and vitamin E. [9] The vitamin E deficiency associated with this disease causes problems such as poor transmission of nerve impulses and muscle weakness.
Inability of pancreas to produce sufficient enzymes necessary for digestion and absorption of nutrients, leading to symptoms such as chronic diarrhea and greasy stools [41] Malabsorption of fats and inability to digest nutrients such as fat-soluble vitamins leads to poor weight gain [ 41 ]