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Hypertrophic osteoarthropathy is a medical condition combining clubbing and periostitis of the small hand joints, especially the distal interphalangeal joints and the metacarpophalangeal joints. Distal expansion of the long bones as well as painful, swollen joints [ 3 ] and synovial villous proliferation are often seen.
Other names are primary hypertrophic osteoarthropathy or Touraine-Solente-Golé syndrome. [2] It is mainly characterized by pachyderma (thickening of the skin), periostosis (excessive bone formation) and finger clubbing (swelling of tissue with loss of normal angle between nail and nail bed). [1] [3] This disease affects more men than women.
Characteristic symptoms including pain, deformity and stiffness. Pain intensity and incapability (limited function) are notably variable and do not correspond with arthritis severity on radiographs. Osteoarthritis of the wrist can be idiopathic , but it is mostly seen as a post-traumatic condition.
A special form of clubbing is hypertrophic pulmonary osteoarthropathy (HPOA), known in continental Europe as Pierre Marie-Bamberger syndrome. This is the combination of clubbing and thickening of periosteum (connective tissue lining of the bones) and synovium (lining of joints), and is often initially diagnosed as arthritis .
Osteoarthritis (OA) is a type of degenerative joint disease that results from breakdown of joint cartilage and underlying bone. [5] [6] It is believed to be the fourth leading cause of disability in the world, affecting 1 in 7 adults in the United States alone. [7]
Examples of periosteal reactive bone in selected specimens of Triceratops. A periosteal reaction can result from a large number of causes, including injury and chronic irritation due to a medical condition such as hypertrophic osteopathy, bone healing in response to fracture, chronic stress injuries, subperiosteal hematomas, osteomyelitis, and cancer of the bone.
The symptoms of post-traumatic arthritis are similar to the ones occurring with osteoarthritis. General symptoms are stiffness , swelling, synovial effusion , pain, redness, tenderness , grinding, instability and intra-articular bleeding of the injured joint .
Facet syndrome is a syndrome in which the facet joints (synovial diarthroses) cause painful symptoms. [1] In conjunction with degenerative disc disease , a distinct but functionally related condition, facet arthropathy is believed to be one of the most common causes of lower back pain.