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  2. Levothyroxine - Wikipedia

    en.wikipedia.org/wiki/Levothyroxine

    Levothyroxine is a synthetic form of thyroxine (T 4), which is secreted by the thyroid gland. Levothyroxine and thyroxine are chemically identical: natural thyroxine is also in the "levo" chiral form, the difference is only in terminological preference. T 4 is biosynthesized from tyrosine. Approximately 5% of the US population suffers from over ...

  3. Thyroxine - Wikipedia

    en.wikipedia.org/wiki/Thyroxine

    Thyroxine, also known as T 4, is a hormone produced by the thyroid gland.It is the primary form of thyroid hormone found in the blood and acts as a prohormone of the more active thyroid hormone, triiodothyronine (T 3). [1]

  4. Therapeutic index - Wikipedia

    en.wikipedia.org/wiki/Therapeutic_index

    The maximum dose is used, rather than a lower dose, to reduce the number of test subjects (and, among other things, the cost of testing), to detect an effect that might occur only rarely. This type of analysis is also used in establishing chemical residue tolerances in foods. Maximum tolerated dose studies are also done in clinical trials.

  5. Thyroid hormones - Wikipedia

    en.wikipedia.org/wiki/Thyroid_hormones

    When pregnant, a woman with a low-functioning thyroid will also need to increase her dosage of thyroid hormone. [16] One exception is that thyroid hormones may aggravate heart conditions, especially in older patients; therefore, doctors may start these patients on a lower dose and work up to a larger one to avoid risk of heart attack.

  6. Thyroid function tests - Wikipedia

    en.wikipedia.org/wiki/Thyroid_function_tests

    Thyroid function tests (TFTs) is a collective term for blood tests used to check the function of the thyroid. [1] TFTs may be requested if a patient is thought to suffer from hyperthyroidism (overactive thyroid) or hypothyroidism (underactive thyroid), or to monitor the effectiveness of either thyroid-suppression or hormone replacement therapy.

  7. Common thyroid drug levothyroxine linked to bone mass loss - AOL

    www.aol.com/lifestyle/common-thyroid-drug...

    Levothyroxine, a drug used to treat hypothyroidism, can lead to reduced bone mass and density in older adults with normal thyroid levels, a small cohort study has shown.

  8. Hypothyroidism - Wikipedia

    en.wikipedia.org/wiki/Hypothyroidism

    Blood free thyroxine and TSH levels are monitored to help determine whether the dose is adequate. This is done 4–8 weeks after the start of treatment or a change in levothyroxine dose. Once the adequate replacement dose has been established, the tests can be repeated after 6 and then 12 months, unless there is a change in symptoms. [8]

  9. Loading dose - Wikipedia

    en.wikipedia.org/wiki/Loading_dose

    A loading dose is most useful for drugs that are eliminated from the body relatively slowly, i.e. have a long systemic half-life. Such drugs need only a low maintenance dose in order to keep the amount of the drug in the body at the appropriate therapeutic level , but this also means that, without an initial higher dose, it would take a long ...

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