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Pantothenic acid (vitamin B 5) is a B vitamin and an essential nutrient. [6] All animals need pantothenic acid in order to synthesize coenzyme A (CoA), which is essential for cellular energy production and for the synthesis and degradation of proteins, carbohydrates, and fats. [6] [7] Pantothenic acid is the combination of pantoic acid and β ...
Pantothenic acid is involved in the oxidation of fatty acids and carbohydrates. Coenzyme A, which can be synthesised from pantothenic acid, is involved in the synthesis of amino acids, fatty acids, ketone bodies, cholesterol, [15] [better source needed] phospholipids, steroid hormones, neurotransmitters (such as acetylcholine), and antibodies. [16]
Vitamin B 5 (pantothenic acid) Vitamin B 6 ; Vitamin B 7 ; Vitamin B 9 (folic acid and folates) Vitamin B 12 ; Vitamin C (ascorbic acid and ascorbates) Vitamin D (calciferols) Vitamin E (tocopherols and tocotrienols) Vitamin K (phylloquinones, menaquinones, and menadiones) Some sources include a fourteenth, choline. [6]
Panthenol (also called pantothenol) is the alcohol analog of pantothenic acid (vitamin B 5), and is thus a provitamin of B 5. In organisms, it is quickly oxidized to pantothenic acid. It is a viscous transparent liquid at room temperature. Panthenol is used in pharmaceutical and children's products as a moisturizer and to hasten wound healing.
The SMVT is a transporter for pantothenic acid (vitamin B5) and biotin (vitamin B7) at the blood–brain barrier. [8] It is also a transporter for lipoic acid [9] and iodide. Transport of these nutrients is competitive [10] and a surplus of a given nutrient may saturate the transporter and prevent the uptake of other nutrients.
Vitamin B5 (pantothenic acid), derived from α,β-dihydroxyisovalerate (a precursor to valine) and aspartic acid, is a component of coenzyme A, which plays a vital role in carbohydrate and amino acid metabolism, as well as fatty acid biosynthesis.
A 100-gram (3 + 1 ⁄ 2-ounce) reference serving of uncooked amaranth grain provides 1,550 kilojoules (371 kilocalories) of food energy, and is a rich source (20% or more of the Daily Value, DV) of protein, dietary fiber, pantothenic acid, vitamin B6, folate, and several dietary minerals (table).
Coenzyme A (CoA, SHCoA, CoASH) is a coenzyme, notable for its role in the synthesis and oxidation of fatty acids, and the oxidation of pyruvate in the citric acid cycle.All genomes sequenced to date encode enzymes that use coenzyme A as a substrate, and around 4% of cellular enzymes use it (or a thioester) as a substrate.
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