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Nikolsky's sign is a clinical dermatological sign, named after Pyotr Nikolsky (1858–1940), a Russian physician who trained and worked in the Russian Empire. The sign is present when slight rubbing of the skin results in exfoliation of the outermost layer.
SSSS is a clinical diagnosis. This is sometimes confirmed by isolation of S. aureus from blood, mucous membranes, or skin biopsy; however, these are often negative. Skin biopsy may show separation of the superficial layer of the epidermis (intraepidermal separation), differentiating SSSS from TEN, wherein the separation occurs at the dermo-epidermal junction (subepidermal separation).
Romaña's sign at Who Named It? painless unilateral periorbital swelling Romberg test: Moritz Heinrich Romberg: neurology: dorsal column lesions, cerebllar lesions, alcohol intoxication: Romberg's sign at Who Named It? inability to maintain posture with eyes closed Rose's sign? vascular medicine: deep vein thrombosis (needed)
The diagnosis is based on involvement of less than 10% of the skin. [2] It is known as TEN when more than 30% of the skin is involved and an intermediate form with 10 to 30% involvement. [3] A positive Nikolsky's sign is helpful in the diagnosis of SJS and TEN. [9] A skin biopsy is helpful, but not required, to establish a diagnosis of SJS and ...
Nikolsky's sign (gentle lateral pressure) on unaffected mucosa or skin raises a bulla. If no lesions are present on examination it may be useful way of demonstrating reduced epithelial adhesion. If no lesions are present on examination it may be useful way of demonstrating reduced epithelial adhesion.
Nikolsky's sign is negative, unlike pemphigus vulgaris, where it is positive. [4] ... Diagnosis consist of at least 2 positive results out of 3 criteria ...
The European Council of Shopping Places named the store as one of seven of those most affected during the war, alongside Nikolsky and Karavan (Kharkiv), Retroville (Kyiv), and Fabrika (Kherson ...
Another test that can aid in a diagnosis of JEB is the positive Nikolsky’s sign. [10] By applying pressure to the skin, transverse movements can indicate slipping between the dermal and epidermal layers. An easier and more definitive test is through polymerase chain reaction (PCR). [9]